Renal-clearable probe with water solubility and photostability for biomarker-activatable detection of acute kidney injuries via NIR-II fluorescence and optoacoustic …

C Zeng, Y Tan, L Sun, Y Long, F Zeng… - Acs Applied Materials & …, 2023 - ACS Publications
Acute kidney injuries (AKI) have serious short-term or long-term complications with high
morbidity and mortality rate, thus posing great health threats. Developing high-performance …

An activatable near-infrared fluorescence probe for in vivo imaging of acute kidney injury by targeting phosphatidylserine and caspase-3

J Weng, Y Wang, Y Zhang, D Ye - Journal of the American …, 2021 - ACS Publications
Renal-clearable and target-responsive near-infrared (NIR) fluorescent imaging probes have
been promising for in vivo diagnosis of acute kidney injury (AKI). However, designing an …

An inherently kidney-targeting near-infrared fluorophore based probe for early detection of acute kidney injury

F Wang, X Jiang, H Xiang, N Wang, Y Zhang… - Biosensors and …, 2021 - Elsevier
Acute kidney injury (AKI) is common in hospital patients. Delayed diagnosis and treatment of
AKI due to the lack of efficient early diagnosis is an important cause of its high mortality …

NIR-II fluorescent biodegradable nanoprobes for precise acute kidney/liver injury imaging and therapy

X Ge, L Su, L Yang, Q Fu, Q Li, X Zhang… - Analytical …, 2021 - ACS Publications
NIR-II fluorescent nanoprobes based on inorganic materials, including rare-earth-doped
nanoparticles, single-walled carbon nanotubes, CdS quantum dots (QDs), gold …

Fluoro‐photoacoustic polymeric renal reporter for real‐time dual imaging of acute kidney injury

P Cheng, W Chen, S Li, S He, Q Miao… - Advanced …, 2020 - Wiley Online Library
Photoacoustic (PA) imaging agents detect disease tissues and biomarkers with increased
penetration depth and enhanced spatial resolution relative to traditional optical imaging, and …

[HTML][HTML] AH2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II …

J Chen, L Chen, Y Wu, Y Fang, F Zeng, S Wu… - Nature …, 2021 - nature.com
Developing high-quality NIR-II fluorophores (emission in 1000–1700 nm) for in vivo imaging
is of great significance. Benzothiadiazole-core fluorophores are an important class of NIR-II …

Ultrabright renal-clearable cyanine-protein nanoprobes for high-quality NIR-II angiography and lymphography

J Xu, T Han, Y Wang, F Zhang, M Li, L Bai, X Wang… - Nano Letters, 2022 - ACS Publications
The renal-clearable aspect of imaging agent with minimum toxicity issues and side effects is
essential for clinical translation, yet clinical near-infrared-I/II (NIR-I/II) fluorophores with timely …

Real-time monitoring renal impairment due to drug-induced AKI and diabetes-caused CKD using an NAG-activatable NIR-II nanoprobe

J Tan, K Yin, Z Ouyang, R Wang, H Pan… - Analytical …, 2021 - ACS Publications
Real-time in vivo optical imaging of kidney function is important for the diagnosis of renal
diseases, such as acute kidney injury (AKI) and chronic kidney disease (CKD), with high …

A Renal‐Clearable Duplex Optical Reporter for Real‐Time Imaging of Contrast‐Induced Acute Kidney Injury

J Huang, Y Lyu, J Li, P Cheng, Y Jiang… - Angewandte …, 2019 - Wiley Online Library
Despite its high morbidity and mortality, contrast‐induced acute kidney injury (CIAKI)
remains a diagnostic dilemma because it relies on in vitro detection of insensitive late‐stage …

Small-molecule photoacoustic imaging probe with aggregation-enhanced amplitude for real-time visualization of acute kidney injury

W Zhang, F Cai, H Xu, Y Wu, X Yu, L Sun… - Analytical …, 2022 - ACS Publications
Acute kidney injury (AKI) has become a growing issue for patients with the extensive use of
all kinds of drugs in clinic. Photoacoustic (PA) imaging provides a noninvasive and real-time …