Resveratrol and brain mitochondria: a review
FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
[HTML][HTML] Resveratrol: A potential therapeutic natural polyphenol for neurodegenerative diseases associated with mitochondrial dysfunction
Most polyphenols can cross blood-brain barrier, therefore, they are widely utilized in the
treatment of various neurodegenerative diseases (ND). Resveratrol, a natural polyphenol …
treatment of various neurodegenerative diseases (ND). Resveratrol, a natural polyphenol …
[HTML][HTML] Resveratrol-mediated regulation of mitochondria biogenesis-associated pathways in neurodegenerative diseases: Molecular insights and potential …
A Shaito, M Al-Mansoob, SMS Ahmad… - Current …, 2023 - ncbi.nlm.nih.gov
Neurodegenerative disorders include different neurological conditions that affect nerve cells,
causing the progressive loss of their functions and ultimately leading to loss of mobility …
causing the progressive loss of their functions and ultimately leading to loss of mobility …
Resveratrol and the mitochondria: From triggering the intrinsic apoptotic pathway to inducing mitochondrial biogenesis, a mechanistic view
Background Mitochondria, the power plants of the cell, are known as a cross-road of
different cellular signaling pathways. These cytoplasmic double-membraned organelles play …
different cellular signaling pathways. These cytoplasmic double-membraned organelles play …
[HTML][HTML] Resveratrol directly binds to mitochondrial complex I and increases oxidative stress in brain mitochondria of aged mice
N Gueguen, V Desquiret-Dumas, G Leman, S Chupin… - PloS one, 2015 - journals.plos.org
Resveratrol is often described as a promising therapeutic molecule for numerous diseases,
especially in metabolic and neurodegenerative disorders. While the mechanism of action is …
especially in metabolic and neurodegenerative disorders. While the mechanism of action is …
[HTML][HTML] Resveratrol protects neurons and the myocardium by reducing oxidative stress and ameliorating mitochondria damage in a cerebral ischemia rat model
R Wang, Y Liu, X Liu, S Jia, J Zhao, D Cui… - Cellular Physiology and …, 2014 - karger.com
Background: Resveratrol has shown potent antioxidant activity in ischemia models. The
present study was performed to determine whether resveratrol protects against cerebral …
present study was performed to determine whether resveratrol protects against cerebral …
Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia
Free radicals are known to cause secondary neuronal damage in cerebral
ischemia/reperfusion (I/R). We investigated here the neuroprotective effect of resveratrol, a …
ischemia/reperfusion (I/R). We investigated here the neuroprotective effect of resveratrol, a …
Resveratrol regulates mitochondrial biogenesis and fission/fusion to attenuate rotenone‐induced neurotoxicity
K Peng, Y Tao, J Zhang, J Wang, F Ye… - Oxidative medicine …, 2016 - Wiley Online Library
It has been confirmed that mitochondrial impairment may underlie both sporadic and familial
Parkinson's disease (PD). Mitochondrial fission/fusion and biogenesis are key processes in …
Parkinson's disease (PD). Mitochondrial fission/fusion and biogenesis are key processes in …
Resveratrol provides neuroprotective effects through modulation of mitochondrial dynamics and ERK1/2 regulated autophagy
KL Lin, KJ Lin, PW Wang, JH Chuang, HY Lin… - Free radical …, 2018 - Taylor & Francis
Mitochondrial dysfunction and oxidative stress are underlying contributors to Parkinson's
disease (PD). The reduction of aberrant proteins and dysfunctional mitochondria through …
disease (PD). The reduction of aberrant proteins and dysfunctional mitochondria through …
[HTML][HTML] Oxidative stress, mitochondrial dysfunction, and neuroprotection of polyphenols with respect to resveratrol in Parkinson's disease
HC Kung, KJ Lin, CT Kung, TK Lin - Biomedicines, 2021 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disease and is
characterized by dopaminergic neuronal loss. The exact pathogenesis of PD is complex and …
characterized by dopaminergic neuronal loss. The exact pathogenesis of PD is complex and …