How neurons develop their morphology is an important question in neurobiology. Here we
describe a new pathway that specifically affects the formation of basal dendrites and axonal …

The precise development of the neocortex is a prerequisite for higher cognitive and
associative functions. Despite numerous advances that have been made in understanding …

Tbr1 is a high-confidence autism spectrum disorder (ASD) gene encoding a transcription
factor with distinct pre-and postnatal functions. Postnatally, Tbr1 conditional knockout (CKO) …

Atypical brain connectivity is a major contributor to the pathophysiology of
neurodevelopmental disorders (NDDs) including autism spectrum disorders (ASDs). TAOK2 …

T‐Brain‐1 (TBR1), a causative gene in autism spectrum disorders (ASDs), encodes a brain‐
specific T‐box transcription factor. It is therefore possible that TBR1 controls the expression …

An understanding of how heterozygous loss-of-function mutations in autism spectrum
disorder (ASD) risk genes, such as TBR1, contribute to ASD remains elusive. Conditional …

Heterozygous loss-of-function mutations in SHANK2 are associated with autism spectrum
disorder (ASD). We generated cortical neurons from induced pluripotent stem cells derived …

The neuron-specific transcription factor T-box brain 1 (TBR1) regulates brain development.
Disruptive mutations in the TBR1 gene have been repeatedly identified in patients with …

Ankrd11 is a potential chromatin regulator implicated in neural development and autism
spectrum disorder (ASD) with no known function in the brain. Here, we show that knockdown …

Genetic risk for autism spectrum disorder (ASD) is associated with hundreds of genes
spanning a wide range of biological functions,,,,–. The alterations in the human brain …