Hydrogels based on Schiff base linkages for biomedical applications

J Xu, Y Liu, S Hsu - Molecules, 2019 - mdpi.com
Schiff base, an important family of reaction in click chemistry, has received significant
attention in the formation of self-healing hydrogels in recent years. Schiff base reversibly …

Fabrication and functionalization of hydrogels through “click” chemistry

S Yigit, R Sanyal, A Sanyal - Chemistry–An Asian Journal, 2011 - Wiley Online Library
Hydrogels are crosslinked polymeric materials that play a vital role in many biomedical
areas such as drug delivery, sensor technology, and tissue engineering. Increasing demand …

Recent advances in hydrogels

D Yang - Chemistry of Materials, 2022 - ACS Publications
Hydrogels are three-dimensional (3D) cross-linked molecular networks, generally polymers,
capable of holding large amounts of water. The network of a hydrogel is established via …

Self-healing hyaluronic acid hydrogels based on dynamic Schiff base linkages as biomaterials

S Li, M Pei, T Wan, H Yang, S Gu, Y Tao, X Liu… - Carbohydrate …, 2020 - Elsevier
Natural hydrogels are widely investigated for biomedical applications because of their
structures similar to extracellular matrix of native tissues, possessing excellent …

Advances in Injectable and Self‐healing Polysaccharide Hydrogel Based on the Schiff Base Reaction

C Mo, L Xiang, Y Chen - Macromolecular Rapid …, 2021 - Wiley Online Library
Injectable hydrogel possesses great application potential in disease treatment and tissue
engineering, but damage to gel often occurs due to the squeezing pressure from injection …

Dynamic protein and polypeptide hydrogels based on Schiff base co-assembly for biomedicine

K Sahajpal, S Shekhar, A Kumar, B Sharma… - Journal of Materials …, 2022 - pubs.rsc.org
Stimuli-responsive biopolymer hydrogels are promising building blocks for biomedical
devices, attributable to their excellent hydrophilicity, biocompatibility, and dynamic …

Preparation of mussel-inspired injectable hydrogels based on dual-functionalized alginate with improved adhesive, self-healing, and mechanical properties

S Yan, W Wang, X Li, J Ren, W Yun, K Zhang… - Journal of Materials …, 2018 - pubs.rsc.org
Injectable hydrogels have aroused much attention for the advantages such as minimally
invasive surgery, avoidance of surgical trauma, and filling and repairing irregularly shaped …

Application of “click” chemistry in biomedical hydrogels

X Li, Y Xiong - ACS omega, 2022 - ACS Publications
Since “click” chemistry was first reported in 2001, it has remained a popular research topic in
the field of chemistry due to its high yield without byproducts, fast reaction rate, simple …

Innovation inspired by nature: Biocompatible self-healing injectable hydrogels based on modified-β-chitin for wound healing

JNI Balitaan, CD Hsiao, JM Yeh, KS Santiago - International Journal of …, 2020 - Elsevier
Remarkable properties of hydrogels are compromised by failure to recover from damage,
bringing their intended functions to an end. To address this, hydrogels can be functionalized …

Toward self-healing hydrogels using one-pot thiol–ene click and borax-diol chemistry

L He, D Szopinski, Y Wu, GA Luinstra… - ACS Macro …, 2015 - ACS Publications
Intrinsic self-healing soft materials such as hydrogels are especially promising for a variety
of medical applications. Multistep preparation of starting functional polymer precursors and …