The lymphatic vasculature forms a vessel network that drains interstitial fluid from tissues
and returns it to the blood. Lymphatic vessels are also an essential part of the body's …

The field of lymphatic research has been recently invigorated by the identification of genes
and mechanisms that control various aspects of lymphatic development. We are beginning …

The lymphatic system is composed of a vascular network of thin-walled capillaries that drain
protein-rich lymph from the extracellular spaces within most organs. A continuous single-cell …

The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of
pathological processes including tissue inflammation and tumor dissemination but is …

The lymph vascular system parallels the blood vasculature and as one of its key functions
returns liquid and solutes to the bloodstream, including macromolecules that have escaped …

Surgery or radiation therapy of metastatic cancer often damages lymph nodes, leading to
secondary lymphedema. Here we show, using a newly established mouse model, that …

The mechanisms of angiogenesis have been studied extensively over the past years. The
focus, however, has been almost exclusively on blood vessels, whereas little effort has been …

Although the process of blood vasculature formation has been well documented, little is
known about lymphatic vasculature development, despite its importance in normal and …

A lack of appropriate in vitro models of three-dimensional lymph vessel growth hampers the
study of lymphangiogenesis. We developed a lymphatic ring assay—a potent, reproducible …

The lymphatic vascular system plays important roles in the maintenance of tissue fluid
homeostasis, in the mediation of the afferent immune response, and in the metastatic spread …