The acute respiratory distress syndrome (ARDS) is a common clinical manifestation of acute
lung injury (ALI) with a high mortality rate. Although improvements in supportive care and …

IMPLICATIONS: Acute respiratory failure is characterized by severe decreases in blood
oxygen. The pattern of blood flow within the lungs can contribute to this problem. This study …

Background: The oleic acid‐induced lung injury (OAI) model is considered to represent the
early phase of acute respiratory distress syndrome (ARDS). Its inherent properties are …

We evaluated the effects of low-dose endotoxin (15 μ g/kg) on the pulmonary and systemic
responses to oleic acid (OA)-induced acute lung injury in dogs. Animals given endotoxin …

Objectives: Oleic acid has been used to induce acute lung injury (ALI) in animals. In patients
with acute respiratory distress syndrome (ARDS), the blood level of oleic acid was …

Recent studies have demonstrated significant synergistic physiological and biochemical
effects between low-dose endotoxin (Etx) administration and oleic acid (OA)-induced canine …

Purpose The present study investigated the effects of positive end-expiratory pressure
(PEEP) on the inflammatory response in two different lung injury models: edematous lung …

Acute lung injury (ALI) or its severe form, acute respiratory distress syndrome (ARDS), is one
of the common causes of acute respiratory failure. Although critical care management has …

Background It is well known that endotoxin causes acute lung injury, resulting in adult
respiratory distress syndrome. Lidocaine pretreatment has recently been shown to attenuate …

Increased abdominal pressure is common in intensive care unit patients. To investigate its
impact on respiration and hemodynamics we applied intraabdominal pressure (aIAP) of 0 …