Respirovirus such as influenza virus infection induces pulmonary anti-viral immune
response, orchestration of innate and adaptive immunity restrain viral infection, otherwise …

Annual epidemics and unexpected pandemics of influenza are threats to human health.
Lung immune and inflammatory responses, such as those induced by respiratory infection …

Neutrophils traffic to the lungs in large numbers during influenza virus infection. Although the
ability of these cells to respond to numerous chemotactic stimuli has been described in other …

Chemokine production by epithelial cells is important for neutrophil recruitment during viral
infection, the appropriate regulation of which is critical for restraining inflammation and …

CXC chemokine ligand 13 (CXCL13), CC chemokine ligand 21 (CCL21), and CCL19 are
constitutively expressed in secondary lymphoid organs, where they control the placement of …

Understanding the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) and clarifying antiviral immunity in hosts are critical aspects for the development of …

Airway epithelial cells are the primary cell type involved in respiratory viral infection. Upon
infection, airway epithelium plays a critical role in host defense against viral infection by …

Rationale Influenza A infections are a leading cause of morbidity and mortality worldwide
especially when associated with secondary pneumococcal infections. Inflammation is …

T-lymphocytes are critical for protection against respiratory infections, such as
Mycobacterium tuberculosis and influenza virus, with chemokine receptors playing an …

Loss of control in the trafficking of immune cells to the inflamed lung tissue contributes to the
pathogenesis of life-threatening acute lung injury (ALI) and its more severe form, acute …