Background Increased intestinal permeability, either due to the exposure to antigens in
asthmatic patients or due to a barrier defect, plays a critical role in susceptibility to …

The article discusses association between serum zonulin presence and severity of atopic
dermatitis in children in the absence of immunoglobulin E (IgE) and eosinophil. Also …

Background Chronic rhinosinusitis (CRS) and asthma are collectively called unified airway
diseases. Periostin has been implicated in the pathophysiologic link of these conditions but …

Background House dust mite (HDM) sublingual immunotherapy (SLIT) has demonstrated
efficacy in clinical trials of patients with asthma. Airway inflammation is a characteristic of …

In this study, we aimed to evaluate the frequency of possible underlying immunodeficiency
responsible for susceptibility to ear, nose, and throat (ENT) infection. One hundred and three …

Background: Allergic rhinitis is characterized by inflammatory cell infiltrate and increased
nasal airflow resistance. Objective: The aim of this study was to evaluate the relationship …

Background Epithelial barrier dysfunction is thought to play a role in many mucosal
diseases, including asthma, chronic rhinosinusitis (CRS), and eosinophilic esophagitis …

Background: An allergen challenge to the airways of sensitized mice causes eosinophilic
airway inflammation and degranulation of goblet cells, which lead to airway obstruction …

Methods RNA and protein were isolated from uncinate tissue (UT) and nasal polyps (NP)
from controls and CRS patients. Normal human bronchial epithelial (NHBE) cells and nasal …

Background: Atopy is the major factor predisposing for the development of allergic airway
diseases. Immunoglobulin E (IgE) levels of children having atopy are elevated as compared …