Combination therapy to treat fungal biofilm-based infections

J Tits, BPA Cammue, K Thevissen - International Journal of Molecular …, 2020 - mdpi.com
An increasing number of people is affected by fungal biofilm-based infections, which are
resistant to the majority of currently-used antifungal drugs. Such infections are often caused …

Antifungal therapy with an emphasis on biofilms

CG Pierce, A Srinivasan, P Uppuluri… - Current opinion in …, 2013 - Elsevier
Highlights•Fungal infections affect an expanding population of immunosuppressed
patients.•The current arsenal of antifungal drugs is exceedingly limited.•Toxicity problems …

[PDF][PDF] Biofilm: A robust and efficient barrier to antifungal chemotherapy

ALS Santos, TP Mello, LS Ramos… - J Antimicrob …, 2015 - academia.edu
Fungal diseases affect a considerable proportion of the worldwide population, ranging in
severity from mild supericial infections to grave invasive diseases [1-7]. he emergence and …

Strength in numbers: antifungal strategies against fungal biofilms

G Ramage, SN Robertson, C Williams - International journal of antimicrobial …, 2014 - Elsevier
Pathogenic fungi have the capacity to form tenacious biofilm structures that are notoriously
unresponsive to antifungal therapies. Fungal biofilms are ubiquitous, located all over the …

Fungal biofilm-a real obstacle against an efficient therapy: lessons from Candida

T Pereira de Mello, L de Souza Ramos… - Current Topics in …, 2017 - ingentaconnect.com
The past decades have witnessed a dramatic increase in invasive fungal infections,
especially caused by different species belonging to the Candida genus. Nowadays, even …

Hybrid combinations containing natural products and antimicrobial drugs that interfere with bacterial and fungal biofilms

SA Zacchino, E Butassi, E Cordisco, LA Svetaz - Phytomedicine, 2017 - Elsevier
Background Biofilms contribute to the pathogenesis of many chronic and difficult-to
eradicate infections whose treatment is complicated due to the intrinsic resistance to …

Combining biofilm-controlling compounds and antibiotics as a promising new way to control biofilm infections

AB Estrela, WR Abraham - Pharmaceuticals, 2010 - mdpi.com
Many bacteria grow on surfaces forming biofilms. In this structure, they are well protected
and often high dosages of antibiotics cannot clear infectious biofilms. The formation and …

[HTML][HTML] Is combined medication with natural medicine a promising therapy for bacterial biofilm infection?

L Zhang, E Liang, Y Cheng, T Mahmood, F Ge… - Biomedicine & …, 2020 - Elsevier
Bacterial biofilms widely exist in nature and seriously threaten global public health. Biofilms
always cause persistent infection and seriously aggravate the occurrence of antibiotic …

Anti-biofilm strategies: how to eradicate Candida biofilms?

A Bink, K Pellens, B PA Cammue… - The open mycology …, 2011 - benthamopen.com
In nature, microorganisms prefer to reside in structured microbial communities, termed
biofilms, rather than as free-floating planktonic cells. Advantageous for the microorganisms …

Combinatorial drug approaches to tackle Candida albicans biofilms

K De Cremer, I Staes, N Delattin… - Expert Review of Anti …, 2015 - Taylor & Francis
The human fungal opportunistic pathogen Candida albicans resides in the human gut,
genitourinary tract and on the skin. The majority of infections caused by C. albicans are …