Lipoprotein (a) and ischemic heart disease—a causal association? A review

PR Kamstrup - Atherosclerosis, 2010 - Elsevier
The aim of this review is to summarize present evidence of a causal association of
lipoprotein (a) with risk of ischemic heart disease (IHD). Evidence for causality includes …

Lipoprotein (a) as a risk factor for ischemic heart disease: metaanalysis of prospective studies

WY Craig, LM Neveux, GE Palomaki… - Clinical …, 1998 - academic.oup.com
Although in vitro studies support a pathophysiologic role for lipoprotein (a)[Lp (a)] in the
development of atherosclerosis, and retrospective studies consistently report that there is a …

Lipoprotein (a) and coronary heart disease

VMG Maher, BG Brown - Current opinion in lipidology, 1995 - journals.lww.com
The role of lipoprotein (a) in the atherosclerotic process is continually being unraveled, and
many of its potential proatherogenic and prothrombotic features have already been …

Lipoprotein (a) and risk of cardiovascular disease--a systematic review and meta analysis of prospective studies.

B Genser, KC Dias, R Siekmeier, T Stojakovic… - Clinical …, 2011 - europepmc.org
Lipoprotein (a) and risk of cardiovascular disease--a systematic review and meta analysis of
prospective studies. - Abstract - Europe PMC Sign in | Create an account https://orcid.org …

Lipoprotein (a): from Causality to Treatment

F Kronenberg - Current Atherosclerosis Reports, 2024 - Springer
Abstract Purpose of Review This paper reviews the evidence why lipoprotein (a)(Lp (a)) is a
causal risk factor for cardiovascular disease and how high Lp (a) concentrations should be …

Lipoprotein (a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop …

S Tsimikas, JL Hall - Journal of the American College of Cardiology, 2012 - jacc.org
Recent published studies have provided increasing evidence that lipoprotein (a)[Lp (a)] may
be a potential causal, genetic, independent risk factor for cardiovascular disease (CVD). Lp …

Lipoprotein (a): a causal independent risk factor for coronary heart disease?

V Gudnason - Current opinion in cardiology, 2009 - journals.lww.com
Although there is highly suggestive evidence for a causal relationship between Lp (a) levels
and CHD, large well prepared 'Mendelian randomization'studies are needed to fully explore …

Lipoprotein (a) and cardiovascular disease

PR Kamstrup - Clinical chemistry, 2021 - academic.oup.com
Background High lipoprotein (a) concentrations present in 10%–20% of the population have
long been linked to increased risk of ischemic cardiovascular disease. It is unclear whether …

Lipoprotein (a): current perspectives

I Gouni-Berthold, HK Berthold - Current vascular …, 2011 - ingentaconnect.com
Recent data from genetic and epidemiological studies strongly support a causal relationship
between elevated lipoprotein (a)[Lp (a)] concentrations and the development of …

Association of LPA variants with risk of coronary disease and the implications for lipoprotein (a)-lowering therapies: a Mendelian randomization analysis

S Burgess, BA Ference, JR Staley, DF Freitag… - JAMA …, 2018 - jamanetwork.com
Importance Human genetic studies have indicated that plasma lipoprotein (a)(Lp [a]) is
causally associated with the risk of coronary heart disease (CHD), but randomized trials of …