Ab initio protein folding is one of the major unsolved problems in computational biology
owing to the difficulties in force field design and conformational search. We developed a …

Depending on whether similar structures are found in the PDB library, the protein structure
prediction can be categorized into template-based modeling and free modeling. Although …

We have developed a new combined approach for ab initio protein structure prediction. The
protein conformation is described as a lattice chain connecting C α atoms, with attached C β …

For single-domain proteins, we examine the completeness of the structures in the current
Protein Data Bank (PDB) library for use in full-length model construction of unknown …

Fragment assembly using structural motifs excised from other solved proteins has shown to
be an efficient method for ab initio protein‐structure prediction. However, how to construct …

The successful prediction of protein structure from amino acid sequence requires two
features: an efficient conformational search algorithm and an energy function with a global …

Ab initio protein folding methods have been developing rapidly over the past few years and,
at the last Critical assessment of methods of protein structure prediction (CASP) meeting, it …

Computationally predicted three-dimensional structure of protein molecules has
demonstrated the usefulness in many areas of biomedicine, ranging from approximate …

We have developed an ab initio protein structure prediction method called chunk-TASSER
that uses ab initio folded supersecondary structure chunks of a given target as well as …

Most protein structural prediction algorithms assemble structures as reduced models that
represent amino acids by a reduced number of atoms to speed up the conformational …