A new liquid chromatography assay with isocratic elution and tandem mass spectrometry
detection (LC–MS/MS) using an electrospray ionization interface in the multiple reaction …

Ertapenem, a carbapenem, relies on time-dependent killing. Therapeutic drug monitoring
(TDM) should be considered, when ertapenem is used in specific populations, to achieve …

Rapid and simple HPLC‐UV and LC‐MS methods were developed and validated for the
quantification of ertapenem (Invanz™) in human plasma. Ertapenem is a unique drug in that …

Carbapanems are a class of β‐lactam antibiotics with broad‐spectrum potency and high β‐
lactamase resistance. Ertapenem, a member of this class, sold under the trade name …

BACKGROUND: Ertapenem (Invanz®) is a newly developed carbapenem β-lactam
antibiotic. LC–MS is the method of choice for therapeutic drug monitoring (TDM) of a variety …

A high-performance liquid chromatography method for the determination of ertapenem in
human plasma using ultraviolet detection (300 nm) was developed and validated. The …

Ertapenem is a new once-a-day antibiotic with excellent coverage of common community
gram negative and gram positive aerobes and anaerobes. It demonstrates nonlinear protein …

Ertapenem is a new carbapenem with a broad spectrum of activity and an extended half-life,
permitting once daily administration. Although high-performance liquid chromatography …

Ertapenem is an important newer broad-spectrum carbapenem antibiotic covering various
infections caused by common gram-positive and-negative aerobes and anaerobes. Due to …

A sensitive HPLC method for the detection and quantification of residual amounts of the 1β‐
methyl carbapenem antibiotic ertapenem and its primary degradates in swabs collected from …