Survival rates for most paediatric cancers have improved at a remarkable pace over the past
four decades. In developed countries, cure is now the probable outcome for most children …

Survival for childhood cancer has increased dramatically over the last 40 years with 5-year
survival rates now approaching 80%. For many diagnostic groups, rapid increases in …

The contributions of cooperative groups to performing large-cohort clinical trials and long-
term survivorship studies have facilitated advances in treatment, supportive care and …

During the past 30 years, changes in the treatment of children and adolescents with cancer
have led to substantial improvements in survival. Although treatment‐related factors have …

Since the 1960s, paediatric oncologists have gradually become better organised in large
study groups and participation in clinical trials is today considered as the standard of care …

The successful treatment of pediatric malignancy by multimodality therapy has improved the
outcome for children with cancer. It has been estimated that 0.1% of individuals 20 years of …

Purpose This report provides an overview of current childhood cancer statistics to facilitate
analysis of the impact of past research discoveries on outcome and provide essential …

Only more recently has it been realized that the intense effort to care for and cure a child with
cancer does not end with survival. Continued surveillance and a variety of interventions …

Although rare, cancer is the leading cause of death from disease in children less than 15
years of age in the United States. 143 With the consistent use of effective multimodality …

Adolescents and young adults (AYA) with cancer are an understudied group. Much of what
is known about long‐term outcomes after AYA cancer has been derived from cohorts of …