Using LongSAGE to detect biomarkers of cervical cancer potentially amenable to optical contrast agent labelling

JM Kneller, T Ehlen, JP Matisic, D Miller… - Biomarker …, 2007 - journals.sagepub.com
Sixteen longSAGE libraries from four different clinical stages of cervical intraepithelial
neoplasia have enabled us to identify novel cell-surface biomarkers indicative of CIN stage …

Multiple biomarkers in molecular oncology. I. Molecular diagnostics applications in cervical cancer detection

DP Malinowski - Expert review of molecular diagnostics, 2007 - Taylor & Francis
The screening for cervical carcinoma and its malignant precursors (cervical neoplasia)
currently employs morphology-based detection methods (Papanicolaou [Pap] smear) in …

Towards improved biomarker studies of cervical neoplasia: effects of precolposcopic procedures on gene expression patterns

SS Wang, A Dasgupta, ME Sherman… - Diagnostic Molecular …, 2005 - journals.lww.com
Among tumor sites, cervical cancer offers an ideal model for investigating differences in
gene expression associated with transitions from normal to precancer and invasion to …

Statistical techniques for diagnosing CIN using fluorescence spectroscopy: SVD and CART

EN Atkinson, MF Mitchell, N Ramanujam… - Journal of Cellular …, 1995 - Wiley Online Library
A quantitative measure of intraepithelial neoplasia which can be made in vivo without tissue
removal would be clinically significant in chemoprevention studies. Our group is working to …

Molecular biomarker-based screening for early detection of cervical cancer.

B Patterson, R Domanik, P Wernke, M Gombrich - Acta cytologica, 2001 - europepmc.org
Objective To evaluate the effectiveness of a molecular biomarker-based screening method
for early detection of cervical cancer. Study design Fluorescent immunochemical labeling …

Biospectroscopy insights into the multi-stage process of cervical cancer development: probing for spectral biomarkers in cytology to distinguish grades

NC Purandare, II Patel, J Trevisan, N Bolger… - Analyst, 2013 - pubs.rsc.org
Cervical cancer screening programmes have greatly reduced the burden associated with
this disease. However, conventional cervical cytology screening still lacks sensitivity and …

Exploratory analysis of quantitative histopathology of cervical intraepithelial neoplasia: Objectivity, reproducibility, malignancy‐associated changes, and human …

M Guillaud, D Cox, K Adler‐Storthz… - Cytometry Part A …, 2004 - Wiley Online Library
Abstract Background Background: As part of a project to evaluate emerging optical
technologies for cervical neoplasia, our group is performing quantitative histopathological …

[HTML][HTML] High resolution analysis of the intracellular proteome of cervical cancer cell lines unveils novel regulators of cervical carcinogenesis

KI Pappa, V Lygirou, G Kontostathi… - Oncology …, 2019 - spandidos-publications.com
Cervical cancer remains the fourth most common and most lethal type of cancer in women,
despite the applied regular screening and prevention strategies, while the available …

Optical technologies and molecular imaging for cervical neoplasia: a program project update

TPH Buys, SB Cantor, M Guillaud, K Adler-Storthz… - Gender medicine, 2012 - Elsevier
There is an urgent global need for effective and affordable approaches to cervical cancer
screening and diagnosis. In developing nations, cervical malignancies remain the leading …

Visible light optical spectroscopy is sensitive to neovascularization in the dysplastic cervix

VTC Chang, SM Bean, PS Cartwright… - … of biomedical optics, 2010 - spiedigitallibrary.org
Neovascularization in cervical intraepithelial neoplasia (CIN) is studied because it is the
precursor to the third most common female cancer worldwide. Diffuse reflectance from 450 …