Oncolytic viruses (OVs) represent a new class of cancer immunotherapeutics. Administration
of OVs to cancer-bearing hosts induces two distinct immunities: antiviral and antitumor …

Oncolytic viruses (OVs) are an emerging class of targeted anticancer therapies designed to
selectively infect, replicate in, and lyse malignant cells without causing harm to normal …

Cancer virotherapy is a paradigm-shifting treatment modality based on virus-mediated
oncolysis and subsequent antitumor immune responses. Clinical trials of currently available …

Cancer Immunotherapy relies on harnessing a patient's immune system to fine-tune specific
anti-tumor responses and ultimately eradicate cancer. Among diverse therapeutic …

Highlights•Oncolytic viruses (OVs) elicit innate and adaptive immune responses against
tumors.•Although the immune system can react against OVs, a functional immune system is …

Oncolytic viruses (OVs) preferentially infect and kill cancer cells without harming normal
cells. OVs can revert cancer-associated immune suppression and initiate clinically …

Oncolytic viruses (OVs), viruses that specifically result in killing tumor cells, represent a
promising class of cancer therapy. Recently, the focus in the OV therapy field has shifted …

Oncolytic viruses (OVs) represent a highly promising treatment strategy for a wide range of
cancers, by mediating both the direct killing of tumor cells as well as mobilization of …

Oncolytic viruses (OVs) constitute a new and promising immunotherapeutic approach
toward cancer treatment. This therapy takes advantage of the natural propensity of most …

Introduction: Over the past decade, the cytolytic capabilities of oncolytic viruses (OVs),
exploited to selectively eliminate neoplastic cells, have become secondary to their use to …