Neurological benefits, clinical challenges, and neuropathologic promise of medical marijuana: A systematic review of cannabinoid effects in multiple sclerosis and …

V Longoria, H Parcel, B Toma, A Minhas, R Zeine - Biomedicines, 2022 - mdpi.com
Despite current therapeutic strategies for immunomodulation and relief of symptoms in
multiple sclerosis (MS), remyelination falls short due to dynamic neuropathologic …

Perspectives on cannabis-based therapy of multiple sclerosis: a mini-review

M Mecha, FJ Carrillo-Salinas, A Feliú… - Frontiers in Cellular …, 2020 - frontiersin.org
The consistency, efficacy, and safety of cannabis-based medicines have been demonstrated
in humans, leading to the approval of the first cannabis-based therapy to alleviate spasticity …

Cannabis and multiple sclerosis—The way forward

T Rudroff, JM Honce - Frontiers in neurology, 2017 - frontiersin.org
The cannabis plant contains up to 110 cannabinoids, though Δ9-tetrahydrocannabinol
(THC) and cannabidiol (CBD) have been the primary focus of medical investigation. THC …

Unveiling the Potential of Cannabinoids in Multiple Sclerosis and the Dawn of Nano-Cannabinoid Medicine

RA Nouh, A Kamal, O Oyewole, WA Abbas, B Abib… - Pharmaceutics, 2024 - mdpi.com
Multiple sclerosis is the predominant autoimmune disorder affecting the central nervous
system in adolescents and adults. Specific treatments are categorized as disease-modifying …

Cannabis and Cannabinoids in Multiple Sclerosis: From Experimental Models to Clinical Practice—A Review

CA Sirbu, R Georgescu, FC Pleşa… - American Journal of …, 2023 - journals.lww.com
Background: As far as 80% of people diagnosed with multiple sclerosis (MS) experience
disabling symptoms in the course of the disease, such as spasticity and neuropathic pain. As …

Multiple sclerosis, cannabinoids, and cognition

P Papathanasopoulos, L Messinis… - The Journal of …, 2008 - Am Neuropsych Assoc
There is increasing interest in the therapeutic potential of cannabis-based medicinal extracts
in multiple sclerosis. Cognitive deficits that have been attributed to long-term heavy …

Emerging properties of cannabinoid medicines in management of multiple sclerosis

G Pryce, D Baker - TRENDS in Neurosciences, 2005 - cell.com
Use of cannabis as a medicine for numerous conditions has a well-documented history
stretching back thousands of years. With the identification of an endogenous system of …

The use of cannabis and cannabinoids in treating symptoms of multiple sclerosis: a systematic review of reviews

S Nielsen, R Germanos, M Weier, J Pollard… - Current neurology and …, 2018 - Springer
Abstract Purpose of Review Pharmaceutical cannabinoids such as nabiximols, nabilone and
dronabinol, and plant-based cannabinoids have been investigated for their therapeutic …

Neuroprotection in experimental autoimmune encephalomyelitis and progressive multiple sclerosis by cannabis-based cannabinoids

G Pryce, DR Riddall, DL Selwood… - Journal of neuroimmune …, 2015 - Springer
Multiple sclerosis (MS) is the major immune-mediated, demyelinating, neurodegenerative
disease of the central nervous system. Compounds within cannabis, notably Δ9 …

Assessment of efficacy and tolerability of medicinal cannabinoids in patients with multiple sclerosis: a systematic review and meta-analysis

MC Torres-Moreno, E Papaseit, M Torrens… - JAMA network …, 2018 - jamanetwork.com
Importance Cannabinoids have antispastic and analgesic effects; however, their role in the
treatment of multiple sclerosis (MS) symptoms is not well defined. Objective To conduct a …