The case against antibiotics and for anti-virulence therapeutics
JA Hotinger, ST Morris, AE May - Microorganisms, 2021 - mdpi.com
Although antibiotics have been indispensable in the advancement of modern medicine,
there are downsides to their use. Growing resistance to broad-spectrum antibiotics is …
there are downsides to their use. Growing resistance to broad-spectrum antibiotics is …
Fresh approaches to anti-infective therapies
C Nathan - Science translational medicine, 2012 - science.org
If discovery of new antibiotics continues to falter while resistance to drugs in clinical use
continues to spread, society's medicine chest will soon lack effective treatments for many …
continues to spread, society's medicine chest will soon lack effective treatments for many …
Antimicrobial resistance: new insights and therapeutic implications
Antimicrobial resistance has not been a new phenomenon. Still, the number of resistant
organisms, the geographic areas affected by emerging drug resistance, and the magnitude …
organisms, the geographic areas affected by emerging drug resistance, and the magnitude …
Counteracting antibiotic resistance: breaking barriers among antibacterial strategies
Introduction: To fight against antibiotic resistance, prevention-only is no longer an
acceptable strategy. The old concept 'one-infection, one-bug, one-drug', genocentrism in …
acceptable strategy. The old concept 'one-infection, one-bug, one-drug', genocentrism in …
Antibiotic resistance: a rundown of a global crisis
B Aslam, W Wang, MI Arshad, M Khurshid… - Infection and drug …, 2018 - Taylor & Francis
The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of
antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial …
antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial …
Therapeutic strategies to combat antibiotic resistance
With multidrug resistant bacteria on the rise, new antibiotic approaches are required.
Although a number of new small molecule antibiotics are currently in the development …
Although a number of new small molecule antibiotics are currently in the development …
Development of antimicrobial agents in the era of new and reemerging infectious diseases and increasing antibiotic resistance
GH Cassell, J Mekalanos - Jama, 2001 - jamanetwork.com
During the past 2 decades, new infectious diseases have appeared and old ones previously
thought to be controlled have reemerged. New and reemerging infectious agents will …
thought to be controlled have reemerged. New and reemerging infectious agents will …
Solving the antibiotic crisis
GD Wright - ACS Infectious Diseases, 2015 - ACS Publications
Antibiotics are essential for both treating and preventing infectious diseases. Paradoxically,
despite their importance as pillars of modern medicine, we are in danger of losing antibiotics …
despite their importance as pillars of modern medicine, we are in danger of losing antibiotics …
Futuristic non-antibiotic therapies to combat antibiotic resistance: A review
The looming problem of resistance to antibiotics in microorganisms is a global health
concern. The drug-resistant microorganisms originating from anthropogenic sources and …
concern. The drug-resistant microorganisms originating from anthropogenic sources and …
The future of antibiotics: emerging technologies and stewardship
JL Fortman, A Mukhopadhyay - Trends in microbiology, 2016 - cell.com
Antibiotic resistance is on the rise while the number of antibiotics being brought to market
continues to drop. While this is a dire situation, a number of emerging technologies have the …
continues to drop. While this is a dire situation, a number of emerging technologies have the …