Exploring the mechanism of diabetic cardiomyopathy treated with Qigui Qiangxin mixture based on UPLC-Q/TOF-MS, network pharmacology and experimental …

Q Han, Y Li, Y Yu, H Yuan, Z Wang, Y Guo, J Shi… - Scientific Reports, 2024 - nature.com
Despite its effectiveness in treating diabetic cardiomyopathy (DCM), Qigui Qiangxin Mixture
(QGQXM) remains unclear in terms of its active ingredients and specific mechanism of …

Exploring the mechanism of anti-chronic heart failure effect of qiweiqiangxin І granules based on metabolomics

W Zhong, Y Li, H Zhong, Y Cheng, Q Chen… - Frontiers in …, 2023 - frontiersin.org
Background: Qiweiqiangxin І granules (QWQX І) is a traditional Chinese medicine
preparation based on the basic theory of traditional Chinese medicine, which produces a …

Traditional Chinese medication qiliqiangxin attenuates diabetic cardiomyopathy via activating PPARγ

X Wu, T Zhang, P Lyu, M Chen, G Ni… - Frontiers in …, 2021 - frontiersin.org
Background: Diabetic cardiomyopathy is the primary complication associated with diabetes
mellitus and also is a major cause of death and disability. Limited pharmacological therapies …

An integrative pharmacology-based strategy to uncover the mechanism of zuogui jiangtang shuxin formula in diabetic cardiomyopathy

Y Huang, Y Zhang, Y Wu, Q Xiang… - … Design, Development and …, 2023 - Taylor & Francis
Purpose This study aimed to explore the mechanism of Zuogui Jiangtang Shuxin formula
(ZGJTSXF) in the treatment of diabetic cardiomyopathy (DCM) by an integrative strategy …

Integrating pharmacokinetics study, network analysis, and experimental validation to uncover the mechanism of qiliqiangxin capsule against chronic heart failure

Y Zhang, M Zhu, F Zhang, S Zhang, W Du… - Frontiers in …, 2019 - frontiersin.org
Objectives: The purpose of this study was to propose an integrated strategy for investigating
the mechanism of Qiliqiangxin capsule (QLQX) to treat chronic heart failure (CHF). Methods …

[HTML][HTML] Qiangxin recipe improves doxorubicin-induced chronic heart failure by enhancing KLF5-mediated glucose metabolism

C Yuan, Z Wu, C Jin, W Cao, Y Dong, J Chen, C Liu - Phytomedicine, 2023 - Elsevier
Background Qiangxin recipe (QXF) is a well-known Chinese herbal medicine commonly
used in Asia for thousands of years to treat cardiovascular diseases, but its underlying …

[HTML][HTML] Effect and mechanism of Tangzhiqing in improving cardiac function in mice with hyperlipidaemia complicated with myocardial ischaemia

Z Song, R Chen, C Wang, G Pan, A Yan, G Xie, Z Yang… - Heliyon, 2023 - cell.com
Purpose Tangzhiqing formula (TZQ) is a traditional Chinese medicine prescribed to treat
lipid metabolism disorders, atherosclerosis, diabetes and diabetic cardiomyopathy …

Multitarget mechanism of Yiqi Jiedu Huayu decoction on diabetic cardiomyopathy based on network pharmacology

C Xuan, Y Luo, Y Xiong, Y Zhang, C Tao… - European Journal of …, 2021 - Elsevier
Abstract Introduction Yiqi Jiedu Huayu decoction (YJHD) is a traditional Chinese medicine
preparation consisting of seven herbs, which has been widely used in the treatment of …

[HTML][HTML] The investigation of potential mechanism of Fuzhengkangfu Decoction against Diabetic myocardial injury based on a combined strategy of network …

M Li, X Liu, Y Wu, X Chen, H Chen, Y Zhong… - Biomedicine & …, 2024 - Elsevier
Abstract Background and Objectives Diabetic cardiomyopathy (DCM) is a cardiac condition
resulting from myocardial damage caused by diabetes mellitus (DM), currently lacking …

Qiliqiangxin Enhances Cardiac Glucose Metabolism and Improves Diastolic Function in Spontaneously Hypertensive Rats

J Wang, Z Li, Y Wang, J Zhang, W Zhao… - Evidence‐Based …, 2017 - Wiley Online Library
Cardiac diastolic dysfunction has emerged as a growing type of heart failure. The present
study aims to explore whether Qiliqiangxin (QL) can benefit cardiac diastolic function in …