Host immunity associated with spontaneous suppression of viremia in therapy-naïve young rhesus macaques following neonatal SHIV infection
TD Evangelous, M Berry, S Venkatayogi… - Journal of …, 2023 - Am Soc Microbiol
We recently found that a new pathogenic chimeric simian-human immunodeficiency virus
(SHIV) elicited heterologous human immunodeficiency virus type-1 (HIV-1) neutralizing …
(SHIV) elicited heterologous human immunodeficiency virus type-1 (HIV-1) neutralizing …
Simian-human immunodeficiency virus SHIV. CH505-infected infant and adult rhesus macaques exhibit similar env-specific antibody kinetics, despite distinct T …
AN Nelson, R Goswami, M Dennis, J Tu… - Journal of …, 2019 - Am Soc Microbiol
Global elimination of pediatric human immunodeficiency virus (HIV) infections will require
the development of novel immune-based approaches, and understanding infant immunity to …
the development of novel immune-based approaches, and understanding infant immunity to …
Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies
B Hora, H Li, X Shen, M Martin, Y Chen, M Berry… - Cell reports, 2023 - cell.com
Infants and children infected with human immunodeficiency virus (HIV)-1 have been shown
to develop neutralizing antibodies (nAbs) against heterologous HIV-1 strains, characteristic …
to develop neutralizing antibodies (nAbs) against heterologous HIV-1 strains, characteristic …
Neutralizing Polyclonal IgG Present during Acute Infection Prevents Rapid Disease Onset in Simian-Human Immunodeficiency Virus SHIVSF162P3-Infected Infant …
JP Jaworski, J Kobie, Z Brower, DC Malherbe… - Journal of …, 2013 - Am Soc Microbiol
Simian-human immunodeficiency virus (SHIV) models for human immunodeficiency virus
(HIV) infection have been widely used in passive studies with HIV neutralizing antibodies …
(HIV) infection have been widely used in passive studies with HIV neutralizing antibodies …
Immune responses and viral persistence in simian/human immunodeficiency virus SHIV. C. CH848-infected rhesus macaques
Chimeric simian/human immunodeficiency viruses (SHIVs) are widely used in nonhuman
primate models to recapitulate human immunodeficiency virus (HIV) infection in humans, yet …
primate models to recapitulate human immunodeficiency virus (HIV) infection in humans, yet …
Immune perturbation following SHIV infection is greater in newborn macaques than in infants
MB Shapiro, T Ordonez, S Pandey, E Mahyari… - JCI insight, 2024 - insight.jci.org
Transmission of HIV-1 to newborns and infants remains high, with 130,000 new infections in
2022 in resource poor settings. Half of HIV-infected newborns, if untreated, progress to …
2022 in resource poor settings. Half of HIV-infected newborns, if untreated, progress to …
[HTML][HTML] Vaccine-induced protection from homologous tier 2 SHIV challenge in nonhuman primates depends on serum-neutralizing antibody titers
MG Pauthner, JP Nkolola, C Havenar-Daughton… - Immunity, 2019 - cell.com
Passive administration of HIV neutralizing antibodies (nAbs) can protect macaques from
hard-to-neutralize (tier 2) chimeric simian-human immunodeficiency virus (SHIV) challenge …
hard-to-neutralize (tier 2) chimeric simian-human immunodeficiency virus (SHIV) challenge …
Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection
MS Parsons, SB Lloyd, WS Lee… - Science translational …, 2017 - science.org
Broadly neutralizing antibodies (BnAbs) protect macaques from cell-free simian/human
immunodeficiency virus (SHIV) challenge, but their efficacy against cell-associated SHIV is …
immunodeficiency virus (SHIV) challenge, but their efficacy against cell-associated SHIV is …
[HTML][HTML] Time dependence of protective post-exposure prophylaxis with human monoclonal antibodies against pathogenic SHIV challenge in newborn macaques
F Ferrantelli, KA Buckley, RA Rasmussen, A Chalmers… - Virology, 2007 - Elsevier
In a primate model of postnatal virus transmission, we have previously shown that 1 h post-
exposure prophylaxis (PEP) with a triple combination of neutralizing monoclonal antibodies …
exposure prophylaxis (PEP) with a triple combination of neutralizing monoclonal antibodies …
Simian-human immunodeficiency virus SHIV. C. CH505 persistence in ART-suppressed infant macaques is characterized by elevated SHIV RNA in the gut and a high …
V Obregon-Perko, KM Bricker, G Mensah… - Journal of …, 2020 - Am Soc Microbiol
Mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) continues to
cause new pediatric cases of infection through breastfeeding, a setting where it is not always …
cause new pediatric cases of infection through breastfeeding, a setting where it is not always …
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