Trisaccharide containing α2, 3-linked sialic acid is a receptor for mumps virus

M Kubota, K Takeuchi, S Watanabe… - Proceedings of the …, 2016 - National Acad Sciences
Mumps virus (MuV) remains an important pathogen worldwide, causing epidemic parotitis,
orchitis, meningitis, and encephalitis. Here we show that MuV preferentially uses a …

Molecular mechanism of the flexible glycan receptor recognition by mumps virus

M Kubota, R Matsuoka, T Suzuki, K Yonekura… - Journal of …, 2019 - Am Soc Microbiol
Mumps virus (MuV) is an important aerosol-transmitted human pathogen causing epidemic
parotitis, meningitis, encephalitis, and deafness. MuV preferentially uses a trisaccharide …

[HTML][HTML] Structural basis for Glycan-receptor binding by mumps virus hemagglutinin-neuraminidase

RE Forgione, C Di Carluccio, M Kubota, Y Manabe… - Scientific reports, 2020 - nature.com
Mumps virus is one of the main cause of respiratory illnesses in humans, especially children.
Among the viral surface glycoproteins, the hemagglutinin–neuraminidase, MuV-HN, plays …

[HTML][HTML] Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation

HJ Nam, B Gurda-Whitaker, WY Gan, S Ilaria… - Journal of biological …, 2006 - ASBMB
Sialic acid binding is required for infectious cell surface receptor recognition by parvovirus
minute virus of mice (MVM). We have utilized a glycan array consisting of∼ 180 different …

[HTML][HTML] Amino acid change 335 E to K affects the sialic-acid-binding and neuraminidase activities of Urabe AM9 mumps virus hemagglutinin–neuraminidase …

J Reyes-Leyva, R Baños, M Borraz-Argüello… - Microbes and …, 2007 - Elsevier
A mutation coding for the amino acid change E335 to K is frequently found in the
hemagglutinin-neuraminidase (HN) gene of Urabe AM9 mumps viruses isolated during post …

Human parainfluenza viruses hPIV1 and hPIV3 bind oligosaccharides with α2-3-linked sialic acids that are distinct from those bound by H5 avian influenza virus …

M Amonsen, DF Smith, RD Cummings… - Journal of virology, 2007 - Am Soc Microbiol
We investigated the binding of human parainfluenza virus types 1 and 3 (hPIV1 and hPIV3,
respectively) to the glycan array of the Consortium for Functional Glycomics and binding and …

[HTML][HTML] Receptor-mediated cell entry of paramyxoviruses: Mechanisms, and consequences for tropism and pathogenesis

CK Navaratnarajah, AR Generous, I Yousaf… - Journal of Biological …, 2020 - ASBMB
Research in the last decade has uncovered many new paramyxoviruses, airborne agents
that cause epidemic diseases in animals including humans. Most paramyxoviruses enter …

Role of sialic acid-containing molecules in paramyxovirus entry into the host cell: a minireview

E Villar, IM Barroso - Glycoconjugate journal, 2006 - Springer
Sialic acid-containing compounds play a key role in the initial steps of the paramyxovirus life
cycle. As enveloped viruses, their entry into the host cell consists of two main events: binding …

Rules and exceptions: sialic acid variants and their role in determining viral tropism

T Stehle, ZM Khan - Journal of virology, 2014 - Am Soc Microbiol
Sialic acids decorate the surfaces of most mammalian cells and are used by many viruses
as attachment receptors. In contrast to other mammals, humans cannot synthesize a version …

Sequence and structure alignment of Paramyxoviridae attachment proteins and discovery of enzymatic activity for a morbillivirus hemagglutinin

JP Langedijk, FJ Daus, JT Van Oirschot - Journal of virology, 1997 - Am Soc Microbiol
On the basis of the conservation of neuraminidase (N) active-site residues in influenza virus
N and paramyxovirus hemagglutinin-neuraminidase (HN), it has been suggested that the …