Tubules injury and immune cell activation are the common pathogenic mechanisms in acute
kidney injury (AKI). However, the exact modes of immune cell activation following tubule …

Tubulointerstitial inflammation is a common characteristic of acute and chronic kidney injury.
However, the mechanism by which the initial injury of tubular epithelial cells (TECs) drives …

Mincle (macrophage-inducible C-type lectin, Clec4e) is a transmembrane pattern
recognition receptor involving the innate immunity, but its role in kidney disease is still …

Sepsis is the leading cause of acute kidney injury (AKI) in critical care patients. A
cornerstone of sepsis-associated AKI is dysregulated inflammation driven by excessive …

Introduction: Acute kidney injury (AKI) is a prevalent medical disorder characterized by a
sudden decline in kidney function, often because of ischemia/reperfusion (I/R) events. It is …

Tubule injury is a characteristic pathological feature of acute kidney injury (AKI) and
determines the prognosis of kidney disease. However, the exact mechanism of tubule injury …

Backgrounds Acute kidney injury (AKI) is characterized by excessive inflammatory response
and apoptosis in tubular epithelial cells. Recent studies suggested that long non-coding …

Activation of endothelial cells plays a key role in septic acute kidney injury (AKI). This study
investigated the role of miRNA in endothelial-induced tubular cell injury in sepsis …

Artesunate is a widely used derivative of artemisinin for malaria. Recent researches have
shown that artesunate has a significant anti‐inflammatory effect on many diseases …

Tubular epithelial cells (TECs) represent the primary site of renal ischemia/reperfusion injury
(RIRI). However, whether the damage of TECs could drive the initiation of inflammation was …