Men diagnosed with low-risk prostate cancer (PC) are increasingly electing active
surveillance (AS) as their initial management strategy. While this may reduce the side effects …

What's known on the subject? and What does the study add? Family history (FH) is a major
risk factor for the development of prostate cancer. The search for genetic variants has led to …

Widespread prostate-specific antigen (PSA) testing notably increased the number of
prostate cancer (PCa) diagnoses. However, about 30% of these patients have low-risk …

Study Type–Prognosis (cohort) Level of Evidence 2a What's known on the subject? and
What does the study add? Men fail active surveillance for a variety of reasons; however, no …

Purpose: We examined the demographic and clinicopathological parameters associated
with the time to convert from active surveillance to treatment among men with prostate …

CONTEXT: Despite widespread screening for prostate cancer (PCa) and major advances in
the treatment of metastatic disease, PCa remains the second most common cause of cancer …

Background Maintaining men on active surveillance for prostate cancer can be challenging.
Although most men who eventually undergo treatment have experienced clinical …

Active surveillance (AS) is an increasingly prevalent treatment choice for low grade prostate
cancer. Eligibility criteria for AS are varied and it is unclear if family history of prostate cancer …

Background: Men with familial prostate cancer and African American men are at risk for
developing prostate cancer at younger ages. Genetic markers predicting early-onset …

BACKGROUND Currently used prognostic markers are limited in their ability to accurately
predict disease progression among patients with localized prostate cancer. We examined 23 …