[HTML][HTML] Physiopathology of the permeability transition pore: Molecular mechanisms in human pathology
Mitochondrial permeability transition (MPT) is the sudden loss in the permeability of the
inner mitochondrial membrane (IMM) to low-molecular-weight solutes. Due to osmotic …
inner mitochondrial membrane (IMM) to low-molecular-weight solutes. Due to osmotic …
[HTML][HTML] The mitochondrial permeability transition pore—Current knowledge of its structure, function, and regulation, and optimized methods for evaluating its …
R Endlicher, Z Drahota, K Štefková, Z Červinková… - Cells, 2023 - mdpi.com
The mitochondrial permeability transition pore (MPTP) is a calcium-dependent, ion non-
selective membrane pore with a wide range of functions. Although the MPTP has been …
selective membrane pore with a wide range of functions. Although the MPTP has been …
Molecular mechanisms and consequences of mitochondrial permeability transition
Mitochondrial permeability transition (mPT) is a phenomenon that abruptly causes the flux of
low molecular weight solutes (molecular weight up to 1,500) across the generally …
low molecular weight solutes (molecular weight up to 1,500) across the generally …
Regulation and pharmacology of the mitochondrial permeability transition pore
The 'mitochondrial permeability transition', characterized by a sudden induced change of the
inner mitochondrial membrane permeability for water as well as for small substances (≤ 1.5 …
inner mitochondrial membrane permeability for water as well as for small substances (≤ 1.5 …
Mitochondrial permeability transition: new findings and persisting uncertainties
Several insults cause the inner mitochondrial membrane to abruptly lose osmotic
homeostasis, hence initiating a regulated variant of cell death known as 'mitochondrial …
homeostasis, hence initiating a regulated variant of cell death known as 'mitochondrial …
The mitochondrial permeability transition pore: an evolving concept critical for cell life and death
G Morciano, N Naumova, P Koprowski… - Biological …, 2021 - Wiley Online Library
In this review, we summarize current knowledge of perhaps one of the most intriguing
phenomena in cell biology: the mitochondrial permeability transition pore (mPTP). This …
phenomena in cell biology: the mitochondrial permeability transition pore (mPTP). This …
[HTML][HTML] Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions
The mitochondrial permeability transition (mPT) describes a Ca2+-dependent and
cyclophilin D (CypD)-facilitated increase of inner mitochondrial membrane permeability that …
cyclophilin D (CypD)-facilitated increase of inner mitochondrial membrane permeability that …
[HTML][HTML] Is mPTP the gatekeeper for necrosis, apoptosis, or both?
Permeabilization of the mitochondrial membranes is a crucial step in apoptosis and
necrosis. This phenomenon allows the release of mitochondrial death factors, which trigger …
necrosis. This phenomenon allows the release of mitochondrial death factors, which trigger …
[HTML][HTML] Mitochondrial permeability transition and oxidative stress
Mitochondrial permeability transition (MPT) is a non-selective inner membrane
permeabilization that may precede necrotic and apoptotic cell death. Although this process …
permeabilization that may precede necrotic and apoptotic cell death. Although this process …
[HTML][HTML] Electrophysiological properties of the mitochondrial permeability transition pores: Channel diversity and disease implication
The mitochondrial permeability transition pore (mPTP) is a channel that, when open, is
responsible for a dramatic increase in the permeability of the mitochondrial inner membrane …
responsible for a dramatic increase in the permeability of the mitochondrial inner membrane …
相关搜索
- human pathology molecular mechanisms
- permeability transition molecular mechanisms
- transition pores disease implication
- transition pore cell life
- permeability transition persisting uncertainties
- permeability transition necrosis and apoptosis
- permeability transition common pathway
- permeability transition oxidative stress
- transition pores channel diversity
- transition pore regulation and pharmacology
- transition pores electrophysiological properties