Excessive exposure to respirable particles of crystalline silica is an occupational health
problem in developing countries and can cause a variety of pulmonary diseases, such as …

The inflammation and fibrosis induced by silica dust are considered to be substantial
responses in silicosis progression. Interleukin-1 beta (IL-1β) plays an important role in silica …

Background The identification of markers that can facilitate the early diagnosis of silicosis
has remained challenging. We evaluated the association of inflammatory markers with the …

Silicosis is the most common occupational lung disease in Egypt where its prevalence rate
ranges from 18.5% to 45.8% among workers exposed to free crystalline silica dust. Despite …

Silicosis is a crippling fibrotic lung disease induced by inhaling crystalline silica. In addition
to fibrosis, silica inhalation by humans is associated with a number of immunological effects …

Inhalation of crystalline silica may lead to acute or chronic silicosis. Although chronic
silicosis is associated with increased incidence/exacerbation of autoimmune disorders, the …

Background Exposure to silica dust may cause inflammatory responses, primarily in the
lungs, although systemic effects have also been reported. Alveolar inflammation can be …

Silicosis is caused by the inhalation of crystalline silica (silicon dioxide, SiO2) in various
forms. This review proposes that the cascade of inflammatory and fibrotic events involved in …

In an examination of the relationship between silicosis and lung function, relevant studies of
silica-exposed workers were reviewed. Smoking, dust exposure, and emphysema are three …

Background It has been established that occupational exposure to silica dust may cause
significant impairment of pulmonary function. To compare the contribution of silicosis and …