Chlorogenic acid prevents diabetic nephropathy by inhibiting oxidative stress and inflammation through modulation of the Nrf2/HO-1 and NF-ĸB pathways

L Bao, J Li, D Zha, L Zhang, P Gao, T Yao… - International …, 2018 - Elsevier
Oxidative and inflammatory damage have been suggested to play important roles in the
pathogenesis of diabetic nephropathy (DN). Chlorogenic acid (CGA) is one of the most …

Chlorogenic acid attenuates lipopolysaccharide-induced acute kidney injury by inhibiting TLR4/NF-κB signal pathway

HY Ye, J Jin, LW Jin, Y Chen, ZH Zhou, ZY Li - Inflammation, 2017 - Springer
Chlorogenic acid (CGA), a polyphenolic compound, exists widely in medicinal herbs, which
has been shown a strong antioxidant and anti-inflammatory effect. This study investigated …

Ellagic acid, an NF-κB inhibitor, ameliorates renal function in experimental diabetic nephropathy

A Ahad, AA Ganai, M Mujeeb, WA Siddiqui - Chemico-Biological …, 2014 - Elsevier
Diabetic nephropathy (DN) is a serious complication confronted by diabetic patients.
Available data indicate that the development of DN is linked to inflammation. In this context …

[PDF][PDF] Sodium butyrate activates NRF2 to ameliorate diabetic nephropathy possibly via inhibition of HDAC

W Dong, Y Jia, X Liu, H Zhang, T Li, W Huang… - J …, 2017 - scholar.archive.org
Oxidative stress contributes to the pathogenesis of diabetic nephropathy (DN). Nuclear
factor erythroid 2-related factor 2 (NRF2) plays a key role in cellular defense against …

High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by …

L Zhang, S Pang, B Deng, L Qian, J Chen, J Zou… - The international journal …, 2012 - Elsevier
Renal hypertrophy and extracellular matrix accumulation are early features of diabetic
nephropathy. Hyperglycemia-induced oxidative stress is implicated in the etiology of …

Epigallocatechin‐3‐Gallate Attenuates Oxidative Stress and Inflammation in Obstructive Nephropathy via NF‐κB and Nrf2/HO‐1 Signalling Pathway Regulation

Y Wang, B Wang, F Du, X Su, G Sun… - Basic & clinical …, 2015 - Wiley Online Library
Oxidative stress and inflammation contribute importantly to the pathogenesis of chronic
kidney disease (CKD). Epigallocatechin‐3‐gallate (EGCG), which is the most abundant and …

D-Saccharic acid 1, 4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and …

S Bhattacharya, P Manna, R Gachhui, PC Sil - Toxicology and applied …, 2013 - Elsevier
Increasing evidence suggests that oxidative stress is involved in the pathogenesis of
diabetic nephropathy (DN) and this can be attenuated by antioxidants. d-Saccharic acid 1, 4 …

BAY 11-7082 ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated oxidative stress and renal inflammation via NF-κB pathway

SR Kolati, ER Kasala, LN Bodduluru… - Environmental …, 2015 - Elsevier
Diabetic nephropathy is a serious microvascular complication for patients associated with
diabetes mellitus. Recent studies have suggested that NF-κB is the main transcription factor …

Cepharanthine and Piperine ameliorate diabetic nephropathy in rats: role of NF-κB and NLRP3 inflammasome

YA Samra, HS Said, NM Elsherbiny, GI Liou… - Life Sciences, 2016 - Elsevier
Aims Hyperglycemia leads to elevation of oxidative stress and proinflammatory cytokines
which are the main causes of diabetic nephropathy (DN). NLRP3 inflammasome and …

[HTML][HTML] Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways

AL Alaofi - Frontiers in Pharmacology, 2020 - frontiersin.org
Diabetic neuropathy (DN) is a complicated inauspicious outcome of diabetes, like other
abnormalities of diabetes the cause of DN is still vague and it may be the result of various …