CRISPR‐Cas system for biomedical diagnostic platforms

Z Wang, W Cui - View, 2020 - Wiley Online Library
Clustered short palindrome repeats with regular intervals, abbreviated as CRISPR, and
functions as a self‐defense system for prokaryotes, detecting particular pathogenic nucleic …

Applications of the CRISPR-Cas system for infectious disease diagnostics

P Li, L Wang, J Yang, LJ Di, J Li - Expert Review of Molecular …, 2021 - Taylor & Francis
Introduction Rapid and accurate diagnostic approaches are essential for impeding the
spread of infectious diseases. This review aims to summarize current progress of clustered …

Biosafety materials: Ushering in a new era of infectious disease diagnosis and treatment with the CRISPR/Cas system

Y Zhang, Z Li, JM Essola, K Ge, X Dai, H He… - Biosafety and …, 2022 - mednexus.org
Despite multiple virus outbreaks over the past decade, including the devastating coronavirus
disease 2019 (COVID-19) pandemic, the lack of accurate and timely diagnosis and …

CRISPR-based diagnostics for detection of pathogens

G Bhattacharjee, N Gohil, NL Lam, V Singh - Progress in Molecular Biology …, 2021 - Elsevier
The improved sensitivity and superior specificity associated with the use of molecular assays
has improved the fate of disease diagnosis by bestowing the clinicians with outcomes that …

CRISPR-Cas-mediated diagnostics

L Li, G Shen, M Wu, J Jiang, Q Xia, P Lin - Trends in Biotechnology, 2022 - cell.com
An ideal molecular diagnostic method should be sensitive, specific, low cost, rapid, portable,
and easy to operate. Traditional nucleic acid detection methods based mainly on PCR …

The applications of CRISPR/Cas system in molecular detection

L Zhou, R Peng, R Zhang, J Li - Journal of cellular and …, 2018 - Wiley Online Library
Abstract The Streptococcus pyogenes CRISPR/Cas system has found widespread
applications as a gene‐editing and regulatory tool for the simultaneous delivery of the Cas9 …

[HTML][HTML] CRISPR as a Diagnostic Tool

S Kim, S Ji, HR Koh - Biomolecules, 2021 - mdpi.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system has
recently gained growing attention as a diagnostic tool due to its capability of specific gene …

CRISPR: A new paradigm of theranostics

N Yadav, J Narang, AK Chhillar, JS Rana - … : Nanotechnology, Biology and …, 2021 - Elsevier
Infectious and hereditary diseases are the primary cause of human mortality globally.
Applications of conventional techniques require significant improvement in sensitivity and …

[HTML][HTML] CRISPR approaches for the diagnosis of human diseases

P Puig-Serra, MC Casado-Rosas… - International Journal of …, 2022 - mdpi.com
CRISPR/Cas is a prokaryotic self-defense system, widely known for its use as a gene-editing
tool. Because of their high specificity to detect DNA and RNA sequences, different CRISPR …

Critical review on where CRISPR meets molecular diagnostics

A Lau, C Ren, LP Lee - Progress in Biomedical Engineering, 2020 - iopscience.iop.org
Simple yet powerful clustered regularly-interspaced short palindromic repeats (CRISPR)
technology has led to the advent of numerous developments in life sciences, biotechnology …