The functional maturation and preservation of hepatic cells derived from human induced
pluripotent stem cells (hiPSCs) are essential to personalized in vitro drug screening and …

The liver is responsible for many metabolic, endocrine and exocrine functions.
Approximately 2 million deaths per year are associated with liver failure. Modern 3D …

We report the first investigation into the bioprinting of human induced pluripotent stem cells
(hiPSCs), their response to a valve-based printing process as well as their post-printing …

A growing number of in vitro hepatic models exist to study human genetics, liver biology,
disease modeling and drug development and range from 2D hepatocytes to 3D multi …

Liver organoids derived from human pluripotent stem cells (PSCs) represent a new type of in
vitro liver model for understanding organ development, disease mechanism and drug …

The liver plays a central role in metabolism. Although many studies have described in vitro
liver models for drug discovery, to date, no model has been described that can stably …

Induced pluripotent stem cell derived hepatocytes (IPSC-Heps) have the potential to reduce
the demand for a dwindling number of primary cells used in applications ranging from …

Hepatocyte-like cells differentiated from human embryonic stem cells (hESCs) or human
induced pluripotent stem cells (hiPSCs) are known to be a useful cell source for drug …

Abstract Three-dimensional (3D) printing of biological material, or 3D bioprinting, is a rapidly
expanding field with interesting applications in tissue engineering and regenerative …

Induced pluripotent stem cells (iPSCs) are new diagnostic and potentially therapeutic tools
to model disease and assess the toxicity of pharmaceutical medications. A common …