[HTML][HTML] TLR9 and COVID-19: a multidisciplinary theory of a multifaceted therapeutic target
GFG Bezemer, J Garssen - Frontiers in Pharmacology, 2021 - frontiersin.org
By mapping the clinical pathophysiology of the novel coronavirus disease 2019 (COVID-19)
against insights from virology, immunology, genomics, epidemiology and pharmacology, it is …
against insights from virology, immunology, genomics, epidemiology and pharmacology, it is …
TLR4 as a therapeutic target for respiratory and neurological complications of SARS-CoV-2
D Kaushik, R Bhandari, A Kuhad - Expert Opinion on Therapeutic …, 2021 - Taylor & Francis
Introduction: The COVID-19 pandemic remains aglobal challenge. While there are mRNA
agents on the horizon as apotential prevention, adefinitive drug therapy is an unmet medical …
agents on the horizon as apotential prevention, adefinitive drug therapy is an unmet medical …
[HTML][HTML] TLRs: innate immune sentries against SARS-CoV-2 infection
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has been responsible for a devastating pandemic since March …
coronavirus 2 (SARS-CoV-2), has been responsible for a devastating pandemic since March …
[HTML][HTML] Toll-like receptor (TLRs) agonists and antagonists for COVID-19 treatments
ZM Liu, MH Yang, K Yu, ZX Lian… - Frontiers in Pharmacology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) rapidly infects
humans and animals which make coronavirus disease 2019 (COVID-19) a grievous …
humans and animals which make coronavirus disease 2019 (COVID-19) a grievous …
[HTML][HTML] Innate receptor activation patterns involving TLR and NLR synergisms in COVID-19, ALI/ARDS and sepsis cytokine storms: a review and model making novel …
R Root-Bernstein - International journal of molecular sciences, 2021 - mdpi.com
Severe COVID-19 is characterized by a “cytokine storm”, the mechanism of which is not yet
understood. I propose that cytokine storms result from synergistic interactions among Toll …
understood. I propose that cytokine storms result from synergistic interactions among Toll …
Role of Toll‐like receptors in the pathogenesis of COVID‐19
S Khanmohammadi, N Rezaei - Journal of medical virology, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), has led to a pandemic since March 2020. The …
syndrome coronavirus 2 (SARS‐CoV‐2), has led to a pandemic since March 2020. The …
Association of TLR3 functional variant (rs3775291) with COVID-19 susceptibility and death: a population-scale study
G Dhangadamajhi, R Rout - Human cell, 2021 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the recent
pandemic of coronavirus disease-19 (COVID-19) has a long, positive-sense, non …
pandemic of coronavirus disease-19 (COVID-19) has a long, positive-sense, non …
Toll-like receptors (TLRs) as therapeutic targets for treating SARS-CoV-2: An immunobiological perspective
Abstract Introduction: Coronavirus disease-19 (COVID-19) caused by SARS-CoV-2 is
presently the biggest threat to mankind throughout the globe. Increasing reports on deaths …
presently the biggest threat to mankind throughout the globe. Increasing reports on deaths …
[HTML][HTML] Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies
YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …
[HTML][HTML] Anti-IL6R role in treatment of COVID-19-related ARDS
SARS-CoV-2 infection is not like the seasonal flu. While the range of symptoms for the two
viruses is similar, the fraction with severe disease appears to be different. For COVID-19 …
viruses is similar, the fraction with severe disease appears to be different. For COVID-19 …
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