[HTML][HTML] RNA modification in cardiovascular disease: implications for therapeutic interventions

C Wang, X Hou, Q Guan, H Zhou, L Zhou… - … and Targeted Therapy, 2023 - nature.com
Cardiovascular disease (CVD) is the leading cause of death in the world, with a high
incidence and a youth-oriented tendency. RNA modification is ubiquitous and indispensable …

Current RNA strategies in treating cardiovascular diseases

SPS Chia, JKS Pang, BS Soh - Molecular Therapy, 2024 - cell.com
Cardiovascular disease (CVD) continues to impose a significant global health burden,
necessitating the exploration of innovative treatment strategies. Ribonucleic acid (RNA) …

RNA modifications in cardiovascular diseases, the potential therapeutic targets

Y Wu, S Zhan, Y Xu, X Gao - Life Sciences, 2021 - Elsevier
More than one hundred RNA modifications decorate the chemical and topological properties
of these ribose nucleotides, thereby executing their biological functions through post …

RNA epigenetics and cardiovascular diseases

LE Dorn, S Tual-Chalot, K Stellos… - Journal of molecular and …, 2019 - Elsevier
Cardiovascular disease (CVD) remains the leading cause of death in the Western world.
Despite advances in the prevention and in the management of CVD, the role of RNA …

RNA modifications in cardiovascular health and disease

A Gatsiou, K Stellos - Nature Reviews Cardiology, 2023 - nature.com
RNA is not always a faithful copy of DNA. Advances in tools enabling the interrogation of the
exact RNA sequence have permitted revision of how genetic information is transferred. We …

[HTML][HTML] Epigenetic signaling and RNA regulation in cardiovascular diseases

A Mongelli, S Atlante, T Bachetti, F Martelli… - International Journal of …, 2020 - mdpi.com
RNA epigenetics is perhaps the most recent field of interest for translational epigeneticists.
RNA modifications create such an extensive network of epigenetically driven combinations …

RNA therapeutics for cardiovascular disease

C Boada, R Sukhovershin, R Pettigrew… - Current opinion in …, 2021 - journals.lww.com
RNA therapeutics is a rapidly emerging field of biotherapeutics based upon a powerful and
versatile platform with a nearly unlimited capacity to address unmet clinical needs. These …

[HTML][HTML] RNA modifications in aging-associated cardiovascular diseases

X Yang, P Gokulnath, HI Lehmann, Z Hou… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide that
bears an enormous healthcare burden and aging is a major contributing factor to CVDs …

RNA-based diagnostic and therapeutic strategies for cardiovascular disease

D Lu, T Thum - Nature Reviews Cardiology, 2019 - nature.com
Cardiovascular diseases are the leading cause of death globally and are associated with
increasing financial expenditure. With the availability of next-generation sequencing …

Non-coding RNAs as epigenetic gene regulators in cardiovascular diseases

W Jiang, DK Agrawal, CS Boosani - Non-Coding RNAs in Cardiovascular …, 2020 - Springer
Epigenetic gene regulations can be considered as de-novo initiation of abnormal molecular
signaling events whose regulation is otherwise required during normal or specific …