Target analysis of volatile organic compounds in exhaled breath for lung cancer discrimination from other pulmonary diseases and healthy persons

M Koureas, P Kirgou, G Amoutzias… - Metabolites, 2020 - mdpi.com
The aim of the present study was to investigate the ability of breath analysis to distinguish
lung cancer (LC) patients from patients with other respiratory diseases and healthy people …

Confounding effect of benign pulmonary diseases in selecting volatile organic compounds as markers of lung cancer

M Wang, J Sheng, Q Wu, Y Zou, Y Hu… - Journal of breath …, 2018 - iopscience.iop.org
Lung cancer (LC) is a leading cause of cancer-related morbidity and mortality globally, and
exhaled breath testing has been considered as a fast, convenient and non-invasive way to …

Comparison of volatile organic compounds from lung cancer patients and healthy controls—Challenges and limitations of an observational study

K Schallschmidt, R Becker, C Jung… - Journal of breath …, 2016 - iopscience.iop.org
This paper outlines the design and performance of an observational study on the profiles of
volatile organic compounds (VOCs) in the breath of 37 lung cancer patients and 23 healthy …

Calculated indices of volatile organic compounds (VOCs) in exhalation for lung cancer screening and early detection

X Chen, KG Muhammad, C Madeeha, W Fu, L Xu, Y Hu… - Lung Cancer, 2021 - Elsevier
Background Breath analysis is a promising noninvasive technique that offers a wide range
of opportunities to facilitate early diagnosis of lung cancer (LC). Method Exhaled breath …

The analysis of volatile organic compounds biomarkers for lung cancer in exhaled breath, tissues and cell lines

Y Wang, Y Hu, D Wang, K Yu, L Wang… - Cancer …, 2012 - content.iospress.com
Background: Volatile organic compounds (VOCs) biomarkers in breath provide a novel,
noninvasive and quick approach to diagnosis lung cancer. The aim of the proposed study …

Quantitative breath analysis of volatile organic compounds of lung cancer patients

G Song, T Qin, H Liu, GB Xu, YY Pan, FX Xiong, KS Gu… - Lung cancer, 2010 - Elsevier
Due to state-of-art analytical techniques, non-invasive exhaled volatile organic compounds
(VOCs) analysis has become a potential method for early diagnosis of lung cancer. We …

Detection of lung cancer with volatile markers in the breath

M Phillips, RN Cataneo, ARC Cummin, AJ Gagliardi… - Chest, 2003 - Elsevier
Study objectives To evaluate volatile organic compounds (VOCs) in the breath as tumor
markers in lung cancer. Alkanes and monomethylated alkanes are oxidative stress products …

Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study

D Poli, P Carbognani, M Corradi, M Goldoni… - Respiratory …, 2005 - Springer
Background Non-invasive diagnostic strategies aimed at identifying biomarkers of lung
cancer are of great interest for early cancer detection. The aim of this study was to set up a …

Prediction of lung cancer using volatile biomarkers in breath

M Phillips, N Altorki, JHM Austin… - Cancer …, 2007 - content.iospress.com
Background: Normal metabolism generates several volatile organic compounds (VOCs) that
are excreted in the breath (eg alkanes). In patients with lung cancer, induction of high-risk …

Application of an artificial neural network model for selection of potential lung cancer biomarkers

T Ligor, Ł Pater, B Buszewski - Journal of Breath Research, 2015 - iopscience.iop.org
Determination of volatile organic compounds (VOCs) in the exhaled breath samples of lung
cancer patients and healthy controls was carried out by SPME-GC/MS (solid phase …