Platelets play a very important role in the pathogenesis of acute vascular events leading to
thrombosis of the coronary and cerebral arteries. Blockage of these arteries leading to …

INTRODUCTION: Large prospective studies must be performed to measure the true effect of
clopidogrel (Plavix) or aspirin (ASA) in prevention of vascular disease. An easy and accurate …

Aware that an estimated 70% of all diagnoses are based to some degree on laboratory data,
JAAPA welcomes you to a new department," Laboratory Insights." Your colleagues in …

We sought to assess how one tablet of non-enteric coated aspirin (325 mg) affects human
platelets in subjects with risk factors for coronary artery disease. Data from 63 individuals …

Consistent levels of platelet inhibition are required to deliver effective antiplatelet therapy.
Growing awareness that not all individuals respond comparably to aspirin has led to the …

Aspirin is widely used to help prevent vascular occlusion caused by atherosclerotic vascular
disease. We used a platelet-aggregation assay (PAA) to evaluate the reliability of a …

The Framingham studies instituted by the National Insti-tutes of Health in the 1950s
identified the major risk factors for the development of cardiovascular disease. Specific lipid …

At antiplatelet doses of 75–325 mg/day, aspirin irreversibly inhibits the platelet
cyclooxygenase (COX)-1-dependent thromboxane A2 (TXA2) formation. This is the …

Biomarker testing for efficacy of therapy is an accepted way for clinicians to individualize
dosing to genetic and/or environmental factors that may be influencing a treatment regimen …

METHODS OF MEASUREMENT OF ASPIRIN-MEDIATED ANTIPLATELET. DEGREE OF
CORRELATION AND AGREEMENT BETWEEN TWO “POINT OF CARE: VERIFYNOW ASPIRIN …