Decoding the olfactory map through targeted transcriptomics links murine olfactory receptors to glomeruli
KW Zhu, SD Burton, MH Nagai, JD Silverman… - Nature …, 2022 - nature.com
Sensory processing in olfactory systems is organized across olfactory bulb glomeruli,
wherein axons of peripheral sensory neurons expressing the same olfactory receptor co …
wherein axons of peripheral sensory neurons expressing the same olfactory receptor co …
Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing
The olfactory system's ability to detect and discriminate between the vast array of chemicals
present in the environment is critical for an animal's survival. In mammals, the first step of this …
present in the environment is critical for an animal's survival. In mammals, the first step of this …
Mapping odorant sensitivities reveals a sparse but structured representation of olfactory chemical space by sensory input to the mouse olfactory bulb
In olfactory systems, convergence of sensory neurons onto glomeruli generates a map of
odorant receptor identity. How glomerular maps relate to sensory space remains unclear …
odorant receptor identity. How glomerular maps relate to sensory space remains unclear …
Uncoupling stimulus specificity and glomerular position in the mouse olfactory system
J Zhang, G Huang, A Dewan, P Feinstein… - Molecular and Cellular …, 2012 - Elsevier
Sensory information is often mapped systematically in the brain with neighboring neurons
responding to similar stimulus features. The olfactory system represents chemical …
responding to similar stimulus features. The olfactory system represents chemical …
Decoding and deorphanizing an olfactory map
H Nishizumi, H Sakano - Nature Neuroscience, 2015 - nature.com
As conversion of odor signals to a two-dimensional map of activated glomeruli in the
olfactory bulb is the key to odor recognition, decoding and deorphanizing of odorant …
olfactory bulb is the key to odor recognition, decoding and deorphanizing of odorant …
[PDF][PDF] A 3D transcriptomics atlas of the mouse nose sheds light on the anatomical logic of smell
MLRT Segura, E Abou Moussa, E Garabello… - Cell reports, 2022 - cell.com
The sense of smell helps us navigate the environment, but its molecular architecture and
underlying logic remain understudied. The spatial location of odorant receptor genes (Olfrs) …
underlying logic remain understudied. The spatial location of odorant receptor genes (Olfrs) …
Deep sequencing of the murine olfactory receptor neuron transcriptome
N Kanageswaran, M Demond, M Nagel… - PloS one, 2015 - journals.plos.org
The ability of animals to sense and differentiate among thousands of odorants relies on a
large set of olfactory receptors (OR) and a multitude of accessory proteins within the …
large set of olfactory receptors (OR) and a multitude of accessory proteins within the …
Multiple perceptible signals from a single olfactory glomerulus
M Smear, A Resulaj, J Zhang, T Bozza… - Nature neuroscience, 2013 - nature.com
Glomeruli are functional units in the olfactory system. The mouse olfactory bulb contains
roughly 2,000 glomeruli, each receiving inputs from olfactory sensory neurons (OSNs) that …
roughly 2,000 glomeruli, each receiving inputs from olfactory sensory neurons (OSNs) that …
Topological reorganization of odor representations in the olfactory bulb
Odors are initially represented in the olfactory bulb (OB) by patterns of sensory input across
the array of glomeruli. Although activated glomeruli are often widely distributed, glomeruli …
the array of glomeruli. Although activated glomeruli are often widely distributed, glomeruli …
Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map
Inputs from olfactory sensory neuron (OSN) axons expressing the same type of odorant
receptor (OR) converge in the glomerulus of the main olfactory bulb. A key marker of mature …
receptor (OR) converge in the glomerulus of the main olfactory bulb. A key marker of mature …