The prevalence of ocular surface immunopathologies is enhanced in the elderly. This
increased prevalence has been attributed to age-related dysregulation of innate and …

Since the last century, advances in healthcare, housing, and education have led to an
increase in life expectancy. Longevity is accompanied by a higher prevalence of age-related …

The ocular surface is the part of the visual system directly exposed to the environment, and it
comprises the cornea, the first refractive tissue layer and its surrounding structures. The …

It has recently been recognized that pathology of age-associated degenerative eye diseases
such as adult macular degeneration (AMD), glaucoma and diabetic retinopathy, have strong …

The prevalence of eye diseases increases considerably with age, resulting in significant
vision impairment. Although the pathobiology of age-related eye diseases has been studied …

Ageing has been defined as a specific individual plasticity and remodeling capacity to the
environment'insults and stimuli. The precise physiology of aging is not entirely understood …

Ocular surface inflammatory disorder (OSID) is a spectrum of disorders that have features of
several etiologies whilst displaying similar phenotypic signs of ocular inflammation. They are …

It has become clear that disorders that were once considered “degenerative” have complex
mechanisms, with many having been shown to have immune mediation as part of the …

On the ocular surface, as in the intestines and airway, the surface epithelium serves a critical
function as the front-line defense of the mucosal innate immune system. Although the …

The eye is regarded as an immune privileged site. Since the presence of a vasculature
would impair vision, the vasculature of the eye is located outside of the central light path. As …