Prevention and Treatment of Respiratory Distress Syndrome in Preterm Neonates.

C McPherson, JA Wambach - Neonatal Network, 2018 - search.ebscohost.com
Respiratory distress syndrome (RDS) impacts a high proportion of preterm neonates,
resulting in significant morbidity and mortality. Advances in pharmacotherapy, specifically …

Corticosteroids and surfactant for prevention of neonatal RDS

B Robertson - Annals of medicine, 1993 - Taylor & Francis
Two main strategies are available for the prevention of neonatal respiratory distress
syndrome (RDS) in cases of preterm delivery: antenatal administration of hormones that …

Neonatal respiratory distress syndrome: an inflammatory disease?

CP Speer - Neonatology, 2011 - karger.com
Surfactant substitution has been a major breakthrough in the treatment of neonatal
respiratory distress syndrome (RDS), primarily caused by a lack of pulmonary surfactant; it …

[HTML][HTML] Timing of surfactant treatment in respiratory distress syndrome

AH van Kaam, HJ Niemarkt, W Onland - Seminars in Fetal and Neonatal …, 2023 - Elsevier
The introduction of exogenous surfactant in the 1980s has resulted in an improved survival
of very preterm infants with respiratory distress syndrome. Randomized controlled trials …

Surfactant therapy: past, present and future

CP Speer, DG Sweet, HL Halliday - Early human development, 2013 - Elsevier
Surfactant replacement in preterm infants with respiratory distress syndrome (RDS) has
been a major therapeutic breakthrough and the most intensively studied intervention in …

Core concepts: respiratory distress syndrome

JB Warren, JDM Anderson - NeoReviews, 2009 - publications.aap.org
Respiratory distress syndrome (RDS) is seen primarily in the preterm neonate and is due
mostly to pulmonary surfactant deficiency. Lung atelectasis leads to ventilation-perfusion …

Mechanisms to explain surfactant responses

AH Jobe - Neonatology, 2006 - karger.com
Surfactant is now standard of care for infants with respiratory distress syndrome. Surfactant
treatments are effective because of complex metabolic interactions between surfactant and …

Pharmacology review: why surfactant works for respiratory distress syndrome

AH Jobe - NeoReviews, 2006 - publications.aap.org
Surfactant treatments have been the standard of care for infants who have respiratory
distress syndrome (RDS) ever since the United States Food and Drug Administration …

Randomized, placebo-controlled trial of human surfactant given at birth versus rescue administration in very low birth weight infants with lung immaturity

TA Merritt, M Hallman, C Berry, M Pohjavuori… - The Journal of …, 1991 - Elsevier
A randomized, placebo-controlled trial of human surfactant given intratracheally at birth
(prophylactic) versus rescue admisistration after the onset of severe respiratory distress …

Beneficial effects of the combined use of prenatal corticosteroids and postnatal surfactant on preterm infants

AH Jobe, BR Mitchell, JH Gunkel - American journal of obstetrics and …, 1993 - Elsevier
OBJECTIVE: Our objective was to test the hypothesis that prenatal maternal corticosteroids
would improve the subsequent response of infants to surfactant treatments. STUDY …