Mitochondria are organelles with a highly dynamic ultrastructure maintained by a delicate
equilibrium between its fission and fusion rates. Understanding the factors influencing this …

Mitochondria are the main powerhouse of the cell, generating ATP through the tricarboxylic
acid cycle (TCA) and oxidative phosphorylation (OXPHOS), which drives myriad cellular …

Within living cells, mitochondria are considered relevant sources of reactive oxygen species
(ROS) and are exposed to reactive nitrogen species (RNS). During the last decade …

Cancer is among the leading causes of death worldwide, and the number of new cases
continues to rise. Despite recent advances in diagnosis and therapeutic strategies, millions …

Mitochondria are an essential component of multicellular life–from primitive organisms, to
highly complex entities like mammals. The importance of mitochondria is underlined by their …

Dynamic change in mitochondrial shape is a cellular process mediated mainly by fission
and fusion of mitochondria. Studies have shown that mitochondrial fission and fusion are …

Mitochondria are key intracellular organelles involved not only in the metabolic state of the
cell, but also in several cellular functions, such as proliferation, Calcium signaling, and lipid …

Mitochondria as crucial organelles regulate cellular energy generation, calcium and redox
homeostasis, and apoptosis. To perform the cellular functions effectively, mitochondria …

Mitochondria are key players in several cellular functions including growth, division, energy
metabolism, and apoptosis. The mitochondrial network undergoes constant remodelling and …

Cancer cell can reprogram their energy production by switching mitochondrial oxidative
phosphorylation to glycolysis. However, mitochondria play multiple roles in cancer cells …