Gastric adenocarcinoma (GAC) is the third leading cause of cancer-related death worldwide.
A high mortality rate and resistance to treatment protocols due to a heterogeneous …

Simple Summary Enhancer of zeste homolog 2 (EZH2) modifies the trimethylation of Lys-27
of histone 3, affecting downstream target genes' expression. It was reported that EZH2 is …

Genetic and epigenetic alterations play an important role in gastric cancer (GC)
pathogenesis. Aberrations of the phosphatidylinositol-3-kinase signaling pathway are well …

Abstract Objectives Long non‐coding RNAs (lncRNAs) are key mediators in various
malignancies. Linc01503 was previously elucidated to promote gastric cancer (GC) cell …

Gastric cancer (GC) is one of the most common malignancies and remains the second
leading cause of cancer-related death worldwide. There is an increasing understanding of …

EZH2 is a core component of the polycomb repressive complex 2 (PRC2), which catalyzes
trimethylation of histone H3 lysine 27 (H3K27me3) and promotes carcinogenesis by …

Gastric carcinoma is one of the major causes of cancer-related mortality worldwide. Early
detection and treatment leads to an excellent prognosis in patients with early gastric cancer …

Cancer is considered one of the major health issues worldwide, and gastric cancer
accounted for 8% of total cases and 10% of total deaths in 2008. Gastric cancer is …

Background STAT3 signaling plays the pivotal role in tumorigenesis through EZH2
epigenetic modification, which enhanced STAT3 activity by increased tyrosine …

Gastric cancer (GC) is one of the deadliest malignancies worldwide. Complex disease
heterogeneity, late diagnosis, and suboptimal therapies result in the poor prognosis of …