Robust identification of common genomic biomarkers from multiple gene expression profiles for the prognosis, diagnosis, and therapies of pancreatic cancer

MB Hossen, MA Islam, MS Reza, MK Kibria… - Computers in Biology …, 2023 - Elsevier
Pancreatic cancer (PC) is one of the leading causes of cancer-related death globally. So,
identification of potential molecular signatures is required for diagnosis, prognosis, and …

Identification of prognostic risk factors for pancreatic cancer using bioinformatics analysis

D Jin, Y Jiao, J Ji, W Jiang, W Ni, Y Wu, R Ni, C Lu… - PeerJ, 2020 - peerj.com
Background Pancreatic cancer is one of the most common malignant cancers worldwide.
Currently, the pathogenesis of pancreatic cancer remains unclear; thus, it is necessary to …

Integrated transcriptomic analysis reveals hub genes involved in diagnosis and prognosis of pancreatic cancer

YY Zhou, LP Chen, Y Zhang, SK Hu, ZJ Dong, M Wu… - Molecular …, 2019 - Springer
Background The hunt for the molecular markers with specificity and sensitivity has been a
hot area for the tumor treatment. Due to the poor diagnosis and prognosis of pancreatic …

Identification of hub genes and analysis of prognostic values in pancreatic ductal adenocarcinoma by integrated bioinformatics methods

Y Lu, C Li, H Chen, W Zhong - Molecular Biology Reports, 2018 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers in the world,
and more molecular mechanisms should be illuminated to meet the urgent need of …

[HTML][HTML] Identification of candidate genes related to pancreatic cancer based on analysis of gene co-expression and protein-protein interaction network

T Zhang, X Wang, Z Yue - Oncotarget, 2017 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is one of the most common causes of cancer mortality worldwide. As
the genetic mechanism of this complex disease is not uncovered clearly, identification of …

Identification and prognostic analysis of biomarkers to predict the progression of pancreatic cancer patients

W Li, T Li, C Sun, Y Du, L Chen, C Du, J Shi… - Molecular Medicine, 2022 - Springer
Background Pancreatic cancer (PC) is a malignancy with a poor prognosis and high
mortality. Surgical resection is the only “curative” treatment. However, only a minority of …

Screening and identification of potential biomarkers for pancreatic cancer: An integrated bioinformatics analysis

S Jafari, M Ravan, I Karimi-Sani, H Aria… - … -Research and Practice, 2023 - Elsevier
Pancreatic cancer is one of the highly invasive and the seventh most common cause of
death among cancers worldwide. To identify essential genes and the involved mechanisms …

Development and validation of a novel metabolic-related signature predicting overall survival for pancreatic cancer

J Huo, L Wu, Y Zang - Frontiers in Genetics, 2021 - frontiersin.org
Recently, growing evidence has revealed the significant effect of reprogrammed metabolism
on pancreatic cancer in relation to carcinogenesis, progression, and treatment. However, the …

Identification of candidate diagnostic and prognostic biomarkers for pancreatic carcinoma

Y Cheng, K Wang, L Geng, J Sun, W Xu, D Liu… - …, 2019 - thelancet.com
Background Pancreatic carcinoma (PC) is one of the most aggressive cancers affecting
human health. It is essential to identify candidate biomarkers for the diagnosis and …

Integrated whole genome microarray analysis and immunohistochemical assay identifies COL11A1, GJB2 and CTRL as predictive biomarkers for pancreatic cancer

D Sun, H Jin, J Zhang, X Tan - Cancer Cell International, 2018 - Springer
Background Pancreatic cancer is characterized by its unsatisfying early detection rate, rapid
disease progression and poor prognosis. Further studies on molecular mechanism and …