Beyond ejection fraction: an integrative approach for assessment of cardiac structure and function in heart failure

M Cikes, SD Solomon - European heart journal, 2016 - academic.oup.com
Left ventricular ejection fraction (LVEF) has been the central parameter used for diagnosis
and management in patients with heart failure. A good predictor of adverse outcomes in …

Assessing left ventricular systolic function: from ejection fraction to strain analysis

BP Halliday, R Senior, DJ Pennell - European Heart Journal, 2021 - academic.oup.com
The measurement of left ventricular ejection fraction (LVEF) is a ubiquitous component of
imaging studies used to evaluate patients with cardiac conditions and acts as an arbiter for …

Left ventricular ejection fraction and heart failure: an indissoluble marriage?

D Mele, M Nardozza, R Ferrari - European Journal of Heart Failure, 2018 - sfera.unife.it
Left ventricular ejection fraction (LVEF) is the most commonly used instrumental parameter
to evaluate patients with heart failure (HF). The major strength of LVEF is that it is a …

Structural and functional phenotyping of the failing heart: is the left ventricular ejection fraction obsolete?

MR Bristow, DP Kao, KK Breathett, NL Altman… - JACC: Heart Failure, 2017 - jacc.org
Diagnosis, prognosis, treatment, and development of new therapies for diseases or
syndromes depend on a reliable means of identifying phenotypes associated with distinct …

Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients

SD Solomon, N Anavekar, H Skali, JJV McMurray… - Circulation, 2005 - Am Heart Assoc
Background—Left ventricular function is a principal determinant of cardiovascular risk in
patients with heart failure. The growing number of patients with preserved systolic function …

[HTML][HTML] Structural and myocardial dysfunction in heart failure beyond ejection fraction

P Severino, V Maestrini, MV Mariani, LI Birtolo… - Heart failure …, 2020 - Springer
Heart failure is a multifaceted syndrome addressing for a high rate of death among the
general population. The common approach to this disease has been always based on the …

Left ventricular remodeling in heart failure: current concepts in clinical significance and assessment

MA Konstam, DG Kramer, AR Patel, MS Maron… - JACC: Cardiovascular …, 2011 - jacc.org
Ventricular remodeling, first described in animal models of left ventricular (LV) stress and
injury, occurs progressively in untreated patients after large myocardial infarction and in …

Changes in left ventricular ejection fraction predict survival and hospitalization in heart failure with reduced ejection fraction

K Breathett, LA Allen, J Udelson, G Davis… - Circulation: Heart …, 2016 - Am Heart Assoc
Background—Left ventricular remodeling, as commonly measured by left ventricular ejection
fraction (LVEF), is associated with clinical outcomes. Although change in LVEF over time …

The many faces of heart failure with preserved ejection fraction

AM Shah, MA Pfeffer - Nature Reviews Cardiology, 2012 - nature.com
By definition, patients with heart failure and preserved ejection fraction are characterized by
a normal or near-normal left ventricular ejection fraction, but marked heterogeneity in the …

Imaging, biomarker, and clinical predictors of cardiac remodeling in heart failure with reduced ejection fraction

A Aimo, HK Gaggin, A Barison, M Emdin, JL Januzzi - JACC: Heart Failure, 2019 - jacc.org
In response to injury, hemodynamic changes, or neurohormonal activation, the heart
undergoes a series of structural and functional changes that have been termed cardiac …