Association of plasma p-tau181 and p-tau231 concentrations with cognitive decline in patients with probable dementia with lewy bodies

MC Gonzalez, NJ Ashton, BF Gomes… - JAMA …, 2022 - jamanetwork.com
Importance Plasma phosphorylated tau (p-tau) has proven to be an accurate biomarker for
Alzheimer disease (AD) pathologic characteristics, offering a less expensive and less …

Correlation of plasma and neuroimaging biomarkers in Alzheimer's disease

AM Brickman, JJ Manly, LS Honig… - Annals of clinical …, 2022 - Wiley Online Library
Blood‐based phosphorylated tau (Ptau) 181 and 217 biomarkers are sensitive and specific
for Alzheimer's disease. In this racial/ethnically diverse cohort study, participants were …

Phospho‐specific plasma p‐tau181 assay detects clinical as well as asymptomatic Alzheimer's disease

S De Meyer, J Vanbrabant… - Annals of clinical …, 2022 - Wiley Online Library
Abstract Objective Plasma phosphorylated‐tau‐181 (p‐tau181) reliably detects clinical
Alzheimer's disease (AD) as well as asymptomatic amyloid‐β (Aβ) pathology, but is …

[HTML][HTML] Diagnostic value of plasma p-tau181, NfL, and GFAP in a clinical setting cohort of prevalent neurodegenerative dementias

S Baiardi, C Quadalti, A Mammana, S Dellavalle… - Alzheimer's research & …, 2022 - Springer
Background Increasing evidence supports the use of plasma biomarkers of
neurodegeneration and neuroinflammation to screen and diagnose patients with dementia …

[HTML][HTML] Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease

NJ Ashton, AL Benedet, TA Pascoal, TK Karikari… - …, 2022 - thelancet.com
Background Phosphorylated tau (p-tau) epitopes in cerebrospinal fluid (CSF) are accurate
biomarkers for a pathological and clinical diagnosis of Alzheimer's disease (AD) and are …

Plasma P-tau181 in Alzheimer's disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer's dementia

S Janelidze, N Mattsson, S Palmqvist, R Smith… - Nature medicine, 2020 - nature.com
Plasma phosphorylated tau181 (P-tau181) might be increased in Alzheimer's disease (AD),
but its usefulness for differential diagnosis and prognosis is unclear. We studied plasma P …

Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic …

EH Thijssen, R La Joie, A Strom, C Fonseca… - The Lancet …, 2021 - thelancet.com
Background Plasma tau phosphorylated at threonine 217 (p-tau217) and plasma tau
phosphorylated at threonine 181 (p-tau181) are associated with Alzheimer's disease tau …

[HTML][HTML] Plasma p-tau181 and p-tau217 in discriminating PART, AD and other key neuropathologies in older adults

L Yu, PA Boyle, S Janelidze, VA Petyuk, T Wang… - Acta …, 2023 - Springer
We examined whether plasma p-tau181 and p-tau217 are specific biomarkers of
pathologically confirmed Alzheimer's disease (AD). In particular, we investigated the utility of …

Discriminative accuracy of plasma phospho-tau217 for Alzheimer disease vs other neurodegenerative disorders

S Palmqvist, S Janelidze, YT Quiroz, H Zetterberg… - Jama, 2020 - jamanetwork.com
Importance There are limitations in current diagnostic testing approaches for Alzheimer
disease (AD). Objective To examine plasma tau phosphorylated at threonine 217 (P-tau217) …

Associations of plasma phospho-tau217 levels with tau positron emission tomography in early Alzheimer disease

S Janelidze, D Berron, R Smith, O Strandberg… - JAMA …, 2021 - jamanetwork.com
Importance There is an urgent need for inexpensive and minimally invasive blood
biomarkers for Alzheimer disease (AD) that could be used to detect early disease changes …