Autophagy has become one of the most important mechanisms of chemotherapy resistance
by supporting the survival of tumor cells under metabolic and therapeutic stress. Here, we …

Autophagy is a double-edged sword in tumor development. Recent studies have found that
miRNAs have an inhibitory effect on the regulation of autophagy. It has been reported that …

Drug resistance, which is closely correlated with an imbalance in apoptosis, endows
colorectal cancer (CRC) with enhanced progression capacity irrespective of the treatment …

Oxaliplatin (OXA) resistance is the major obstacle to the anticancer effects of chemotherapy
in colorectal cancer (CRC) patients. MicroRNAs (miRNAs) play an important role in the …

Introduction Previous studies have found that miRNAs play a key role in drug resistance.
Multiple reports show that miRNAs act as regulators in colorectal cancer (CRC) cells, but the …

Chemotherapy is an important treatment modality for gastric cancer (GC); however, it usually
fails because of drug resistance, especially multidrug resistance (MDR). Previously, we …

Abstract miR-17-5p has been found to be involved in the proliferation and metastasis of
colorectal cancer (CRC), and N 6-methyladenosine (m6A) modification is the most common …

Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of
cancer‑associated mortalities worldwide. MicroRNAs (miRNAs/miRs) serve important roles …

Evidence demonstrate that p53 mutations and microRNAs (miRs) are important components
of 5-FU resistance in colorectal cancer (CRC). miR-338-3p has been reported associated …

Gastric cancer is a prevalent cancer and chemotherapy is a main treatment for patients.
Docetaxel is commonly used as a chemotherapeutic drug for gastric cancer patients. With …