The heart as a target for deltamethrin toxicity: Inhibition of Nrf2/HO-1 pathway induces oxidative stress and results in inflammation and apoptosis

X Yang, Y Fang, J Hou, X Wang, J Li, S Li, X Zheng… - Chemosphere, 2022 - Elsevier
As a synthetic pyrethroid pesticide, deltamethrin (DLM) is widely employed in veterinary
medicine and farming, and DLM-triggered oxidative stress largely causes serious harm to …

Toxicological effects of deltamethrin on quail cerebrum: weakened antioxidant defense and enhanced apoptosis

J Li, H Jiang, P Wu, S Li, B Han, Q Yang, X Wang… - Environmental …, 2021 - Elsevier
Deltamethrin is the most common type II synthetic pyrethroid insecticide, and has posed
widespread residues to environment. However, whether deltamethrin has potential toxic …

Cadmium induced cardiac inflammation in chicken (Gallus gallus) via modulating cytochrome P450 systems and Nrf2 mediated antioxidant defense

K Guo, J Ge, C Zhang, MW Lv, Q Zhang, M Talukder… - Chemosphere, 2020 - Elsevier
Cadmium (Cd) has been implicated in the pathogenesis of inflammation, myocardial
infarction, angiocardiopathy, even cancers. However, it is unknown that Cd-induced cardiac …

Triptolide-induced oxidative stress involved with Nrf2 contribute to cardiomyocyte apoptosis through mitochondrial dependent pathways

J Zhou, C Xi, W Wang, X Fu, L Jinqiang, Y Qiu, J Jin… - Toxicology letters, 2014 - Elsevier
Triptolide (TP), a major active ingredient extracted from the widely used Chinese herb
Tripterygium wilfordii Hook f.(TWHF), has been demonstrated to possess various biological …

Deltamethrin induces apoptosis in cerebrum neurons of quail via promoting endoplasmic reticulum stress and mitochondrial dysfunction

S Li, P Wu, B Han, Q Yang, X Wang, J Li… - Environmental …, 2022 - Wiley Online Library
Deltamethrin (DLM) is a widely used and highly effective insecticide. DLM exposure is
harmful to animal and human. Quail, as a bird model, has been widely used in the field of …

[HTML][HTML] Exploring the liver fibrosis induced by deltamethrin exposure in quails and elucidating the protective mechanism of resveratrol

S Li, X Zheng, X Zhang, H Yu, B Han, Y Lv, Y Liu… - Ecotoxicology and …, 2021 - Elsevier
Deltamethrin (DLM) is widely used in agriculture and the prevention of human insect-borne
diseases. However, the molecular mechanism of DLM induced liver injury remains unclear …

Genistein protects against doxorubicin‐induced cardiotoxicity through Nrf‐2/HO‐1 signaling in mice model

Z Bai, Z Wang - Environmental toxicology, 2019 - Wiley Online Library
Doxorubicin (DOX)‐induced cardiomyopathy is a lethal disease. DOX‐induced cardiotoxic
effects are attributed towards increased redox status and apoptotic signaling. In this study …

Co-exposure to molybdenum and cadmium evokes necroptosis and decreases apoptosis in duck myocardium

H Liu, X Dai, S Xu, H Guo, J Zhu, S Wang, Y Wu… - Science of The Total …, 2023 - Elsevier
Superfluous molybdenum (Mo) and cadmium (Cd) in the environment are detrimental to
organisms through their accumulation. The NF-κB/TNF-α axis plays a vital part in regulating …

Exposure to diclofop-methyl induces cardiac developmental toxicity in zebrafish embryos

Z Cao, Y Huang, J Xiao, H Cao, Y Peng, Z Chen… - Environmental …, 2020 - Elsevier
Diclofop-methyl (DM) is one of the most widely used herbicides in agriculture production and
has been frequently detected in both freshwater and environments, even agricultural …

[HTML][HTML] Dihydroartemisinin alleviates deoxynivalenol induced liver apoptosis and inflammation in piglets

J Li, Y Bai, K Ma, Z Ren, J Li, J Zhang… - … and Environmental Safety, 2022 - Elsevier
Deoxynivalenol (DON) is one of the mycotoxins that contaminate cereals and feed, thereby
endangering human and animal health. Dihydroartemisinin (DHA), a derivative of …