PTX3, a humoral pattern recognition molecule, in innate immunity, tissue repair, and cancer
C Garlanda, B Bottazzi, E Magrini… - Physiological …, 2018 - journals.physiology.org
Innate immunity includes a cellular and a humoral arm. PTX3 is a fluid-phase pattern
recognition molecule conserved in evolution which acts as a key component of humoral …
recognition molecule conserved in evolution which acts as a key component of humoral …
[HTML][HTML] PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer
PTX3 is an essential component of the humoral arm of innate immunity, playing a
nonredundant role in resistance against selected microbes and in the regulation of …
nonredundant role in resistance against selected microbes and in the regulation of …
The long pentraxin PTX3 as a link between innate immunity, tissue remodeling, and cancer
A Doni, M Stravalaci, A Inforzato, E Magrini… - Frontiers in …, 2019 - frontiersin.org
The innate immune system comprises a cellular and a humoral arm. Humoral pattern
recognition molecules include complement components, collectins, ficolins, and pentraxins …
recognition molecules include complement components, collectins, ficolins, and pentraxins …
The dual complexity of PTX3 in health and disease: a balancing act?
E Magrini, A Mantovani, C Garlanda - Trends in molecular medicine, 2016 - cell.com
The humoral arm of innate immunity is complex and includes various molecules that serve
as markers of inflammation with complementary characteristics, such as the short pentraxins …
as markers of inflammation with complementary characteristics, such as the short pentraxins …
The pattern recognition receptor PTX3 is recruited at the synapse between dying and dendritic cells, and edits the cross-presentation of self, viral, and tumor antigens
P Baruah, A Propato, IE Dumitriu, P Rovere-Querini… - Blood, 2006 - ashpublications.org
Pentraxins are soluble pattern recognition receptors with a dual role: protection against
extracellular microbes and autoimmunity. The mechanisms by which they accomplish these …
extracellular microbes and autoimmunity. The mechanisms by which they accomplish these …
The long pentraxin PTX3 at the crossroads between innate immunity and tissue remodelling
Innate immunity represents the first line of defence against pathogens and plays key roles in
the activation and orientation of the adaptive immune response. The innate immune system …
the activation and orientation of the adaptive immune response. The innate immune system …
An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode
A Doni, T Musso, D Morone, A Bastone… - Journal of Experimental …, 2015 - rupress.org
Pentraxin 3 (PTX3) is a fluid-phase pattern recognition molecule and a key component of the
humoral arm of innate immunity. In four different models of tissue damage in mice, PTX3 …
humoral arm of innate immunity. In four different models of tissue damage in mice, PTX3 …
Pentraxins in the activation and regulation of innate immunity
Humoral fluid phase pattern recognition molecules (PRM s) are a key component of the
activation and regulation of innate immunity. Humoral PRM s are diverse. We focused on the …
activation and regulation of innate immunity. Humoral PRM s are diverse. We focused on the …
The “sweet” side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation
A Inforzato, PC Reading, E Barbati, B Bottazzi… - Frontiers in …, 2013 - frontiersin.org
Innate immunity represents the first line of defense against pathogens and plays key roles in
activation and orientation of the adaptive immune response. The innate immune system …
activation and orientation of the adaptive immune response. The innate immune system …
Pathogen recognition by the long pentraxin PTX3
Innate immunity represents the first line of defence against pathogens and plays key roles in
activation and orientation of the adaptive immune response. The innate immune system …
activation and orientation of the adaptive immune response. The innate immune system …
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