The genetic landscape of choroid plexus tumors in children and adults

C Thomas, P Soschinski, M Zwaig… - Neuro …, 2021 - academic.oup.com
Abstract Background Choroid plexus tumors (CPTs) are intraventricular brain tumors
predominantly arising in children but also affecting adults. In most cases, driver mutations …

Epigenetics impacts upon prognosis and clinical management of choroid plexus tumors

C Thomas, K Metrock, U Kordes, M Hasselblatt… - Journal of Neuro …, 2020 - Springer
Purpose Choroid plexus tumors comprise of choroid plexus papilloma (CPP, WHO grade I),
atypical choroid plexus papilloma (aCPP, WHO grade II) and choroid plexus carcinoma …

Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups

DM Merino, A Shlien, A Villani, M Pienkowska… - Clinical Cancer …, 2015 - AACR
Purpose: To investigate molecular alterations in choroid plexus tumors (CPT) using a
genome-wide high-throughput approach to identify diagnostic and prognostic signatures …

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups

C Thomas, M Sill, V Ruland, A Witten… - Neuro …, 2016 - academic.oup.com
Background Choroid plexus tumors are intraventricular neoplasms derived from the choroid
plexus epithelium. A better knowledge of molecular factors involved in choroid plexus tumor …

Pediatric choroid plexus carcinoma: biologically and clinically in need of new perspectives

W Zaky, JL Finlay - Pediatric Blood & Cancer, 2018 - Wiley Online Library
Choroid plexus (CP) carcinoma is a rare pediatric brain neoplasm. Recent studies have
highlighted the potential of genome‐wide methylation and gene expression profiling to …

DNA methylation signature is prognostic of choroid plexus tumor aggressiveness

M Pienkowska, S Choufani, AL Turinsky, T Guha… - Clinical …, 2019 - Springer
Background Histological grading of choroid plexus tumors (CPTs) remains the best
prognostic tool to distinguish between aggressive choroid plexus carcinoma (CPC) and the …

Choroid plexus tumors in adult and pediatric populations: the Cleveland Clinic and University Hospitals experience

M Bahar, H Hashem, T Tekautz, S Worley… - Journal of Neuro …, 2017 - Springer
Choroid plexus tumors (CPT) are rare neoplasms accounting for 1–4% of all pediatric brain
tumors. They are divided into choroid plexus papilloma (CPP), atypical choroid plexus …

High-resolution genomic analysis does not qualify atypical plexus papilloma as a separate entity among choroid plexus tumors

AS Japp, M Gessi, M Messing-Jünger… - … of Neuropathology & …, 2015 - academic.oup.com
Choroid plexus tumors are rare neoplasms that mainly affect children. They include
papillomas, atypical papillomas, and carcinomas. Detailed genetic studies are rare, and …

Choroid plexus tumors in children less than 36 months: the Canadian Pediatric Brain Tumor Consortium (CPBTC) experience

L Lafay-Cousin, D Keene, AS Carret, C Fryer… - Child's Nervous …, 2011 - Springer
Background Choroid plexus tumors (CPT) are rare pediatric tumors. A population-based
study on choroid plexus carcinoma (CPC) and choroid plexus papilloma (CPP) was carried …

Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis

V Ruland, S Hartung, U Kordes, JE Wolff… - Genes …, 2014 - Wiley Online Library
Choroid plexus carcinoma is a malignant brain tumor predominantly occurring in young
children. Only limited data are available regarding the underlying molecular genetic …