[HTML][HTML] Still'dwelling in the possibility'-critical update on stem cell therapy for acute on chronic liver failure

CA Philips, P Augustine - World Journal of Stem Cells, 2020 - ncbi.nlm.nih.gov
Stem cells therapy could improve survival in patients with liver failure. Studies on stem cell
therapy and related growth factors in decompensated cirrhosis has been on the forefront but …

Clinical performance of stem cell therapy in patients with acute-on-chronic liver failure: a systematic review and meta-analysis

R Xue, Q Meng, J Dong, J Li, Q Yao, Y Zhu… - Journal of Translational …, 2018 - Springer
Background Stem cell therapy has been applied in the treatment of acute-on-chronic liver
failure (ACLF). However, its clinical efficiency is still debatable. The aim of this systematic …

Bone Marrow Mesenchymal Stem Cells in Acute‐on‐Chronic Liver Failure Grades 2 and 3: A Phase I‐II Randomized Clinical Trial

FC Schacher, A Martins Pezzi da Silva… - Canadian Journal of …, 2021 - Wiley Online Library
Introduction. Acute‐on‐chronic liver failure (ACLF) is an acute liver decompensation in
cirrhotic patients, which leads to organ failures and high short‐term mortality. The treatment …

[HTML][HTML] Stem cell therapies for liver failure and cirrhosis

Z Zhang, FS Wang - Journal of Hepatology, 2013 - Elsevier
Liver failure and cirrhosis occur as a result of a variety of chronic hepatic injuries. They
display sequential and overlapping severe pathogenic processes that include severe …

The development of stem cell-based treatment for liver failure

T Zhu, Y Li, Y Guo, C Zhu - Current Stem Cell Research & …, 2017 - ingentaconnect.com
Background: Liver failure is a devastating clinical syndrome with a persistently mortality rate
despite advanced care. Orthotopic liver transplantation protected patients from hepatic …

[HTML][HTML] Acute liver failure: A systematic review and network meta-analysis of optimal type of stem cells in animal models

JF Ma, JP Gao, ZW Shao - World Journal of Stem Cells, 2023 - ncbi.nlm.nih.gov
BACKGROUND The therapeutic effects of various stem cells in acute liver failure (ALF) have
been demonstrated in preclinical studies. However, the specific type of stem cells with the …

Clinical effectiveness of cell therapies in patients with chronic liver disease and acute-on-chronic liver failure: a systematic review protocol

NN Than, CL Tomlinson, D Haldar, AL King, D Moore… - Systematic reviews, 2016 - Springer
Background Chronic liver disease (CLD) is a major health burden worldwide. Liver cirrhosis,
a form of CLD is the fifth most common cause of death in the UK. Acute-on-chronic liver …

A brief analysis of mesenchymal stem cells as biological drugs for the treatment of acute-on-chronic liver failure (ACLF): safety and potency

Y Feng, AT Wang, HH Jia, M Zhao… - Current Stem Cell …, 2020 - ingentaconnect.com
Acute-on-Chronic Liver Failure (ACLF) is characterized by acute exacerbation of chronic
hepatitis, organ failure, high mortality, and poor prognosis. At present, the clinical methods of …

Therapeutic effect and safety of stem cell therapy for chronic liver disease: a systematic review and meta-analysis of randomized controlled trials

GP Zhou, YZ Jiang, LY Sun, ZJ Zhu - Stem Cell Research & Therapy, 2020 - Springer
Background Stem cell therapy is becoming an emerging therapeutic option for chronic liver
disease (CLD). However, whether stem cell therapy is more effective than conventional …

Exploring the most promising stem cell therapy in liver failure: a systematic review

J AdiwinataPawitan - Stem Cells International, 2019 - Wiley Online Library
Background. Alternative approaches to transplantation for liver failure are needed. One of
the alternative approaches is stem cell therapy. However, stem cell therapy in liver failure is …