Identification and development of a novel 5-gene diagnostic model based on immune infiltration analysis of osteoarthritis
Background Osteoarthritis (OA), which is due to the progressive loss and degeneration of
articular cartilage, is the leading cause of disability worldwide. Therefore, it is of great …
articular cartilage, is the leading cause of disability worldwide. Therefore, it is of great …
Screening of osteoarthritis diagnostic markers based on immune-related genes and immune infiltration
WH Yuan, QQ Xie, KP Wang, W Shen, XF Feng… - Scientific Reports, 2021 - nature.com
Osteoarthritis (OA) is a chronic degenerative disease of the bone and joints. Immune-related
genes and immune cell infiltration are important in OA development. We analyzed immune …
genes and immune cell infiltration are important in OA development. We analyzed immune …
Identification of key biomarkers and immune infiltration in the synovial tissue of osteoarthritis by bioinformatics analysis
W Cai, H Li, Y Zhang, G Han - PeerJ, 2020 - peerj.com
Background Osteoarthritis (OA) is the most common chronic degenerative joint disease and
is mainly characterized by cartilage degeneration, subcartilage bone hyperplasia …
is mainly characterized by cartilage degeneration, subcartilage bone hyperplasia …
Identification of potential biomarkers for differential diagnosis between rheumatoid arthritis and osteoarthritis via integrative genome‑wide gene expression profiling …
R Zhang, X Yang, J Wang, L Han… - Molecular …, 2019 - spandidos-publications.com
The present study aimed to identify potential novel biomarkers in synovial tissue obtained
from patients with Rheumatoid Arthritis (RA) and Osteoarthritis (OA) for differential diagnosis …
from patients with Rheumatoid Arthritis (RA) and Osteoarthritis (OA) for differential diagnosis …
Analysis of differentially expressed genes between rheumatoid arthritis and osteoarthritis based on the gene co‑expression network
QY Lu, QH Han, X Li, ZC Li… - Molecular …, 2014 - spandidos-publications.com
The aim of the current study was to investigate disease‑associated genes and related
molecular mechanisms of osteoarthritis (OA) and rheumatoid arthritis (RA). Using GSE7669 …
molecular mechanisms of osteoarthritis (OA) and rheumatoid arthritis (RA). Using GSE7669 …
[HTML][HTML] Bioinformatics-led discovery of osteoarthritis biomarkers and inflammatory infiltrates
X Hu, S Ni, K Zhao, J Qian, Y Duan - Frontiers in Immunology, 2022 - frontiersin.org
The molecular mechanisms of osteoarthritis, the most common chronic disease, remain
unexplained. This study aimed to use bioinformatic methods to identify the key biomarkers …
unexplained. This study aimed to use bioinformatic methods to identify the key biomarkers …
Identification of four-gene signature to diagnose osteoarthritis through bioinformatics and machine learning methods
Z Chen, W Wang, Y Zhang, Y Hua - Cytokine, 2023 - Elsevier
Background Although osteoarthritis (OA) is one of the most prevalent joint disorders,
effective biomarkers to diagnose OA are still unavailable. This study aimed to acquire some …
effective biomarkers to diagnose OA are still unavailable. This study aimed to acquire some …
Identification of differentially expressed genes, signaling pathways and immune infiltration in rheumatoid arthritis by integrated bioinformatics analysis
Y Ge, L Zhou, Z Chen, Y Mao, T Li, P Tong, L Shan - Hereditas, 2021 - Springer
Background The disability rate associated with rheumatoid arthritis (RA) ranks high among
inflammatory joint diseases. However, the cause and potential molecular events are as yet …
inflammatory joint diseases. However, the cause and potential molecular events are as yet …
[HTML][HTML] Weighted gene co-expression network analysis reveals specific modules and hub genes related to immune infiltration of osteoarthritis
J Cao, H Ding, J Shang, L Ma, Q Wang… - Annals of translational …, 2021 - ncbi.nlm.nih.gov
Background The incidence of osteoarthritis (OA), a chronic degenerative disease, is
increasing every year. There is no effective clinical treatment for OA and the pathological …
increasing every year. There is no effective clinical treatment for OA and the pathological …
Three hematologic/immune system-specific expressed genes are considered as the potential biomarkers for the diagnosis of early rheumatoid arthritis through …
Q Cheng, X Chen, H Wu, Y Du - Journal of translational medicine, 2021 - Springer
Background Rheumatoid arthritis (RA) is the most common chronic autoimmune connective
tissue disease. However, early RA is difficult to diagnose due to the lack of effective …
tissue disease. However, early RA is difficult to diagnose due to the lack of effective …
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