The thymus is the organ responsible for T cell development and the formation of the
adaptive immunity function. Its multicellular environment consists mainly of the different …

The thymus is critical in establishing and maintaining the appropriate microenvironment for
promoting the development and selection of T cells. The function and structure of the thymus …

T-cell development in the thymus is a stepwise process, mediated by a variety of stromal
cells in different regions of the organ. Although the cellular composition of the thymic …

The thymus is unique in its ability to support the maturation of phenotypically and
functionally distinct T cell sub-lineages. Through its combined production of MHC-restricted …

The thymus is a complex epithelial organ in which thymocyte development is dependent
upon the sequential contribution of morphologically and phenotypically distinct stromal cell …

In the mature thymus, thymocyte maturation depends on interactions with different thymic
epithelial subtypes in a three-dimensional thymic architecture. However, the molecular …

The thymus is an intricate primary lymphoid organ, wherein bone marrow–derived lymphoid
progenitor cells are induced to develop into functionally competent T cells that express a …

The thymus is a crucial organ for the development of T cells. T cell progenitors first migrate
from the bone marrow into the thymus. During the journey to become a mature T cell …

The thymus plays a crucial role in the development of T lymphocytes providing an inductive
microenvironment in which committed progenitors undergo proliferation, T-cell receptor …

The thymus is the primary lymphoid organ responsible for the generation and maturation of
T cells. Thymic epithelial cells (TECs) account for the majority of thymic stromal components …