Monitoring T lymphocyte differentiation is essential for understanding T cell fate regulation
and advancing adoptive T cell immunotherapy. However, current biomarker analysis …

The sensitivity and speed with which the immune system reacts to host disruption is
unrivaled by any detection method for pathogenic biomarkers or infectious signatures …

Genetically engineered T cells are a powerful new modality for cancer immunotherapy.
However, their clinical application for solid tumors is challenging, and crucial knowledge on …

Label-free single-cell analytics have been developed for understanding the collective
immune response mechanism of immune cells. However, it remains difficult to analyze the …

The identification of T and B lymphocytes has relied on using antibodies against different
biomarkers as the gold standard. Emerging small molecule-based fluorescent probes have …

In recent years, the expression and progression of programmed cell death ligand 1 (PD-L1)
as an immunomarker in the context of a cell metabolic environment has gained significant …

Monitoring specific immune cells in vivo will provide significant information for improving the
therapeutic effect of immunotherapy. Herein, the in vivo two-color fluorescence molecular …

The activation of the immune system is critical for cancer immunotherapy and treatments of
inflammatory diseases. Non-invasive visualization of immunoactivation is designed to …

Detection of circulating tumor cells (CTCs) could be widely used for early diagnosis and real-
time monitoring of tumor progression in liquid biopsy samples. Compared with normal cells …

Fluorescence imaging microscopy is an essential tool in biomedical research. Meanwhile,
various fluorescent probes are available for the staining of cells, cell membranes, and …