Algorithms for inferring haplotypes
T Niu - Genetic Epidemiology: The Official Publication of the …, 2004 - Wiley Online Library
Haplotype phase information in diploid organisms provides valuable information on human
evolutionary history and may lead to the development of more efficient strategies to identify …
evolutionary history and may lead to the development of more efficient strategies to identify …
A partition-ligation-combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis (http://analysis. bio-x. cn)
Haplotypic information in diploid organisms provides valuable information on human
evolutionary history and plays an important role in identifying a candidate gene in the …
evolutionary history and plays an important role in identifying a candidate gene in the …
A new statistical method for haplotype reconstruction from population data
M Stephens, NJ Smith, P Donnelly - The American Journal of Human …, 2001 - cell.com
Current routine genotyping methods typically do not provide haplotype information, which is
essential for many analyses of fine-scale molecular-genetics data. Haplotypes can be …
essential for many analyses of fine-scale molecular-genetics data. Haplotypes can be …
Haplotyping methods for pedigrees
Haplotypes provide valuable information in the study of diseases, complex traits, population
histories, and evolutionary genetics. With the dramatic increase in the number of available …
histories, and evolutionary genetics. With the dramatic increase in the number of available …
Comparison of the accuracy of methods of computational haplotype inference using a large empirical dataset
RM Adkins - BMC genetics, 2004 - Springer
Background Analyses of genetic data at the level of haplotypes provide increased accuracy
and power to infer genotype-phenotype correlations and evolutionary history of a locus …
and power to infer genotype-phenotype correlations and evolutionary history of a locus …
Comparisons of two methods for haplotype reconstruction and haplotype frequency estimation from population data
Haplotype reconstruction is an important issue, both in population genetics and in the
identification of complex disease genes. Stephens et al.(2001) proposed a new statistical …
identification of complex disease genes. Stephens et al.(2001) proposed a new statistical …
Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data
D Fallin, NJ Schork - The American Journal of Human Genetics, 2000 - cell.com
Haplotype analyses have become increasingly common in genetic studies of human
disease because of their ability to identify unique chromosomal segments likely to harbor …
disease because of their ability to identify unique chromosomal segments likely to harbor …
Partition-ligation–expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms
The mapping of SNPs in human genomes has generated a lot of interest from both the
biomedical research community and industry. In conjunction with SNP mapping, researchers …
biomedical research community and industry. In conjunction with SNP mapping, researchers …
Understanding the accuracy of statistical haplotype inference with sequence data of known phase
Statistical methods for haplotype inference from multi‐site genotypes of unrelated
individuals have important application in association studies and population genetics …
individuals have important application in association studies and population genetics …
A comparison of bayesian methods for haplotype reconstruction from population genotype data
M Stephens, P Donnelly - The American Journal of Human Genetics, 2003 - cell.com
In this report, we compare and contrast three previously published Bayesian methods for
inferring haplotypes from genotype data in a population sample. We review the methods …
inferring haplotypes from genotype data in a population sample. We review the methods …