Inhibitory inputs tune the light response properties of dopaminergic amacrine cells in mouse retina

GS Newkirk, M Hoon, RO Wong… - Journal of …, 2013 - journals.physiology.org
Dopamine (DA) is a neuromodulator that in the retina adjusts the circuitry for visual
processing in dim and bright light conditions. It is synthesized and released from retinal …

Mapping physiological inputs from multiple photoreceptor systems to dopaminergic amacrine cells in the mouse retina

X Zhao, KY Wong, DQ Zhang - Scientific reports, 2017 - nature.com
In the vertebrate retina, dopamine is synthesized and released by a specialized type of
amacrine cell, the dopaminergic amacrine cell (DAC). DAC activity is stimulated by rods …

Light-dependent pathways for dopaminergic amacrine cell development and function

T Munteanu, KJ Noronha, AC Leung, S Pan, JA Lucas… - Elife, 2018 - elifesciences.org
Retinal dopamine is a critical modulator of high acuity, light-adapted vision and
photoreceptor coupling in the retina. Dopaminergic amacrine cells (DACs) serve as the sole …

Intraretinal signaling by ganglion cell photoreceptors to dopaminergic amacrine neurons

DQ Zhang, KY Wong, PJ Sollars… - Proceedings of the …, 2008 - National Acad Sciences
Retinal dopaminergic amacrine neurons (DA neurons) play a central role in reconfiguring
retinal function according to prevailing illumination conditions, yet the mechanisms by which …

Rod photoreceptor activation alone defines the release of dopamine in the retina

V Pérez-Fernández, N Milosavljevic, AE Allen… - Current Biology, 2019 - cell.com
Retinal dopamine is released by a specialized subset of amacrine cells in response to light
and has a potent influence on how the retina responds to, and encodes, visual information …

Multiple cone pathways are involved in photic regulation of retinal dopamine

SN Qiao, Z Zhang, CP Ribelayga, YM Zhong… - Scientific reports, 2016 - nature.com
Dopamine is a key neurotransmitter in the retina and plays a central role in the light adaptive
processes of the visual system. The sole source of retinal dopamine is dopaminergic …

Disruption in dopaminergic innervation during photoreceptor degeneration

E Ivanova, CW Yee… - Journal of Comparative …, 2016 - Wiley Online Library
Dopaminergic amacrine cells (DACs) release dopamine in response to light‐driven synaptic
inputs, and are critical to retinal light adaptation. Retinal degeneration (RD) compromises …

Dopamine D1 and D4 receptors contribute to light adaptation in ON-sustained retinal ganglion cells

MD Flood, ED Eggers - Journal of Neurophysiology, 2021 - journals.physiology.org
The adaptation of ganglion cells to increasing light levels is a crucial property of the retina.
The retina must respond to light intensities that vary by 10–12 orders of magnitude, but the …

[HTML][HTML] Role of dopamine in retinal function

E Popova - Webvision: The Organization of the Retina and Visual …, 2020 - ncbi.nlm.nih.gov
Dopamine (DA) is the major catecholamine in all vertebrate retinas including man. All
vertebrates have dopaminergic neurons identified as amacrine cells (ACs) and …

Functional heterogeneity of retinal dopaminergic neurons underlying their multiple roles in vision

DQ Zhang, TR Zhou, DG McMahon - Journal of Neuroscience, 2007 - Soc Neuroscience
Dopaminergic neurons play key roles in the CNS, mediating basic mechanisms of vision,
movement, motivation, and mood. The most accessible dopaminergic neurons of the …