[HTML][HTML] Isopentyl caffeate as a promising drug for the treatment of leishmaniasis: An in silico and in vivo study
WS Mota, SSC Oliveira, MM Pereira, DP Souza… - Current Research in …, 2024 - Elsevier
Leishmaniasis is recognised as the second largest parasitic disease worldwide and yet a
neglected disease. The current pharmacological treatments are associated with significant …
neglected disease. The current pharmacological treatments are associated with significant …
[HTML][HTML] Analysis of the mechanisms of action of isopentenyl caffeate against Leishmania
SSC Oliveira, CSF Marques, DP de Sousa… - Biochimie, 2021 - Elsevier
Leishmaniasis is a neglected parasitic disease for which the conventional treatment can be
considered inefficient and extremely aggressive, generating several and severe side effects …
considered inefficient and extremely aggressive, generating several and severe side effects …
[HTML][HTML] Study on Experimental Leishmanicidal Activity and in silico of Cytochalasin B
AO Feitosa, FJN Ferreira, HPC Brigido… - Journal of the Brazilian …, 2019 - SciELO Brasil
Leishmaniasis is a neglected infectious disease caused by different species of the
Leishmania parasite and is one of the major public health problems in developing countries …
Leishmania parasite and is one of the major public health problems in developing countries …
Antileishmanial activity evaluation of a natural amide and its synthetic analogs against Leishmania (V.) braziliensis: an integrated approach in vitro and in silico
MA da Silva, HH Fokoue, SN Fialho… - Parasitology …, 2021 - Springer
Leishmaniasis is considered a neglected disease, which makes it an unattractive market for
the pharmaceutical industry; hence, efforts in the search for biologically active substances …
the pharmaceutical industry; hence, efforts in the search for biologically active substances …
Eugenol-Rich Essential Oil from Pimenta dioica: In Vitro and In Vivo Potentialities against Leishmania amazonensis
Pimenta dioica L. is one the most recognized species with diverse biological activities. In this
study, in vitro activity and in vivo efficacy of essential oil from P. dioica (EO-Pd) was …
study, in vitro activity and in vivo efficacy of essential oil from P. dioica (EO-Pd) was …
In silico and in vitro comparative activity of green tea components against Leishmania infantum
S Khademvatan, K Eskandari, K Hazrati-Tappeh… - Journal of global …, 2019 - Elsevier
Objectives Green tea contains a predominant set of polyphenolic compounds with biological
activities. The aim of this study was to investigate the antileishmanial activities of the main …
activities. The aim of this study was to investigate the antileishmanial activities of the main …
Antiprotozoal Activity of Thymoquinone (2-Isopropyl-5-methyl-1,4-benzoquinone) for the Treatment of Leishmania major-Induced Leishmaniasis: In Silico and In Vitro …
Leishmaniasis, a neglected tropical parasitic disease (NTPD), is caused by various
Leishmania species. It transmits through the bites of the sandfly. The parasite is evolving …
Leishmania species. It transmits through the bites of the sandfly. The parasite is evolving …
Antileishmanial Effects of Bunium Persicum Crude Extract, Essential Oil, and Cuminaldehyde on Leishmania Major: In Silico and In Vitro Properties
Purpose Cuminaldehyde (CA), an oxidized aldehyde monoterpene, is a major essential oil
component in cumin seeds, which has shown different promising medical effects. In this …
component in cumin seeds, which has shown different promising medical effects. In this …
[HTML][HTML] In vitro evaluation, in silico studies and toxicological assay of some xanthones as potential Leishmania donovani inhibitors
Xanthones are naturally occurring compounds that exist in some higher plants, fungi and
lichen. Natural and synthetic xanthones have shown diverse biological and pharmacological …
lichen. Natural and synthetic xanthones have shown diverse biological and pharmacological …
Flavopereirine—An Alkaloid Derived from Geissospermum vellosii—Presents Leishmanicidal Activity In Vitro
JV da Silva e Silva, HP Cordovil Brigido… - Molecules, 2019 - mdpi.com
Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs,
low efficacy of alternative treatments, and resistance of the parasite. This work assesses the …
low efficacy of alternative treatments, and resistance of the parasite. This work assesses the …